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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability.
Hodson C, Low JKK, van Twest S, Jones SE, Swuec P, Murphy V, Tsukada K, Fawkes M, Bythell-Douglas R, Davies A, Holien JK, O'Rourke JJ, Parker BL, Glaser A, Parker MW, Mackay JP, Blackford AN, Costa A, Deans AJ. Hodson C, et al. Among authors: holien jk. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2109093119. doi: 10.1073/pnas.2109093119. Proc Natl Acad Sci U S A. 2022. PMID: 35115399 Free PMC article.
Direct involvement of the TEN domain at the active site of human telomerase.
Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: holien jk. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.
Oncogenic protein interfaces: small molecules, big challenges.
Nero TL, Morton CJ, Holien JK, Wielens J, Parker MW. Nero TL, et al. Among authors: holien jk. Nat Rev Cancer. 2014 Apr;14(4):248-62. doi: 10.1038/nrc3690. Epub 2014 Mar 13. Nat Rev Cancer. 2014. PMID: 24622521 Review.
56 results