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Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice.
De Logu F, Nassini R, Hegron A, Landini L, Jensen DD, Latorre R, Ding J, Marini M, Souza Monteiro de Araujo D, Ramírez-Garcia P, Whittaker M, Retamal J, Titiz M, Innocenti A, Davis TP, Veldhuis N, Schmidt BL, Bunnett NW, Geppetti P. De Logu F, et al. Among authors: ramirez garcia p. Nat Commun. 2022 Feb 3;13(1):646. doi: 10.1038/s41467-022-28204-z. Nat Commun. 2022. PMID: 35115501 Free PMC article.
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Ramírez-García PD, Retamal JS, Shenoy P, Imlach W, Sykes M, Truong N, Constandil L, Pelissier T, Nowell CJ, Khor SY, Layani LM, Lumb C, Poole DP, Lieu T, Stewart GD, Mai QN, Jensen DD, Latorre R, Scheff NN, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Davis TP, Bunnett NW. Ramírez-García PD, et al. Nat Nanotechnol. 2019 Dec;14(12):1150-1159. doi: 10.1038/s41565-019-0568-x. Epub 2019 Nov 4. Nat Nanotechnol. 2019. PMID: 31686009 Free PMC article.
Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice.
Retamal JS, Grace MS, Dill LK, Ramirez-Garcia P, Peng S, Gondin AB, Bennetts F, Alvi S, Rajasekhar P, Almazi JG, Carbone SE, Bunnett NW, Davis TP, Veldhuis NA, Poole DP, McIntyre P. Retamal JS, et al. Among authors: ramirez garcia p. Lab Invest. 2021 Jul;101(7):851-864. doi: 10.1038/s41374-021-00593-7. Epub 2021 Apr 15. Lab Invest. 2021. PMID: 33859334 Free PMC article.
Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain.
Latorre R, Ramírez-Garcia PD, Hegron A, Grace JL, Retamal JS, Shenoy P, Tran M, Aurelio L, Flynn B, Poole DP, Klein-Cloud R, Jensen DD, Davis TP, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Bunnett NW. Latorre R, et al. Among authors: ramirez garcia pd. Biomaterials. 2022 Jun;285:121536. doi: 10.1016/j.biomaterials.2022.121536. Epub 2022 Apr 28. Biomaterials. 2022. PMID: 35533442 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36775556
31 results