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The IGFBP3/TMEM219 pathway regulates beta cell homeostasis.
D'Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, Loretelli C, Bertuzzi F, Antonioli B, Cardarelli F, El Essawy B, Solini A, Gerling IC, Bianchi C, Becchi G, Mazzucchelli S, Corradi D, Fadini GP, Foschi D, Markmann JF, Orsi E, Škrha J Jr, Camboni MG, Abdi R, James Shapiro AM, Folli F, Ludvigsson J, Del Prato S, Zuccotti G, Fiorina P. D'Addio F, et al. Among authors: bertuzzi f. Nat Commun. 2022 Feb 3;13(1):684. doi: 10.1038/s41467-022-28360-2. Nat Commun. 2022. PMID: 35115561 Free PMC article.
Long-term beneficial effect of islet transplantation on diabetic macro-/microangiopathy in type 1 diabetic kidney-transplanted patients.
Fiorina P, Folli F, Bertuzzi F, Maffi P, Finzi G, Venturini M, Socci C, Davalli A, Orsenigo E, Monti L, Falqui L, Uccella S, La Rosa S, Usellini L, Properzi G, Di Carlo V, Del Maschio A, Capella C, Secchi A. Fiorina P, et al. Among authors: bertuzzi f. Diabetes Care. 2003 Apr;26(4):1129-36. doi: 10.2337/diacare.26.4.1129. Diabetes Care. 2003. PMID: 12663585 Free article.
Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: a comparison between kidney-pancreas and kidney-alone transplantation.
Fiorina P, Folli F, Maffi P, Placidi C, Venturini M, Finzi G, Bertuzzi F, Davalli A, D'Angelo A, Socci C, Gremizzi C, Orsenigo E, La Rosa S, Ponzoni M, Cardillo M, Scalamogna M, Del Maschio A, Capella C, Di Carlo V, Secchi A. Fiorina P, et al. Among authors: bertuzzi f. Transplantation. 2003 Apr 27;75(8):1296-301. doi: 10.1097/01.TP.0000061788.32639.D9. Transplantation. 2003. PMID: 12717219
Disproportionate hyperproinsulinemia, beta-cell restricted prohormone convertase 2 deficiency, and cell cycle inhibitors expression by human islets transplanted into athymic nude mice: insights into nonimmune-mediated mechanisms of delayed islet graft failure.
Davalli AM, Perego L, Bertuzzi F, Finzi G, La Rosa S, Blau A, Placidi C, Nano R, Gregorini L, Perego C, Capella C, Folli F. Davalli AM, et al. Among authors: bertuzzi f. Cell Transplant. 2008;17(12):1323-36. doi: 10.3727/096368908787648137. Cell Transplant. 2008. PMID: 19364070 Free article.
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death.
Di Cairano ES, Davalli AM, Perego L, Sala S, Sacchi VF, La Rosa S, Finzi G, Placidi C, Capella C, Conti P, Centonze VE, Casiraghi F, Bertuzzi F, Folli F, Perego C. Di Cairano ES, et al. Among authors: bertuzzi f. J Biol Chem. 2011 Apr 22;286(16):14007-18. doi: 10.1074/jbc.M110.183517. Epub 2011 Feb 18. J Biol Chem. 2011. PMID: 21335552 Free PMC article.
Long-term Effect of Islet Transplantation on Glycemic Variability.
Bertuzzi F, De Carlis L, Marazzi M, Rampoldi AG, Bonomo M, Antonioli B, Tosca MC, Galuzzi M, Lauterio A, Fava D, Dorighet P, De Gasperi A, Colussi G. Bertuzzi F, et al. Cell Transplant. 2018 May;27(5):840-846. doi: 10.1177/0963689718763751. Epub 2018 Jun 5. Cell Transplant. 2018. PMID: 29871516 Free PMC article.
Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes.
Tezza S, Ben Nasr M, D'Addio F, Vergani A, Usuelli V, Falzoni S, Bassi R, Dellepiane S, Fotino C, Rossi C, Maestroni A, Solini A, Corradi D, Giani E, Mameli C, Bertuzzi F, Pezzolesi MG, Wasserfall CH, Atkinson MA, Füchtbauer EM, Ricordi C, Folli F, Di Virgilio F, Pileggi A, Dhe-Paganon S, Zuccotti GV, Fiorina P. Tezza S, et al. Among authors: bertuzzi f. Diabetes. 2018 Oct;67(10):2038-2053. doi: 10.2337/db17-1227. Epub 2018 Jul 31. Diabetes. 2018. PMID: 30065030 Free PMC article.
161 results