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Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation.
Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B. Moustaki A, et al. Among authors: crawford jc. Sci Immunol. 2022 Feb 4;7(68):eabf6136. doi: 10.1126/sciimmunol.abf6136. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 35119937 Free PMC article.
Quantifiable predictive features define epitope-specific T cell receptor repertoires.
Dash P, Fiore-Gartland AJ, Hertz T, Wang GC, Sharma S, Souquette A, Crawford JC, Clemens EB, Nguyen THO, Kedzierska K, La Gruta NL, Bradley P, Thomas PG. Dash P, et al. Among authors: crawford jc. Nature. 2017 Jul 6;547(7661):89-93. doi: 10.1038/nature22383. Epub 2017 Jun 21. Nature. 2017. PMID: 28636592 Free PMC article.
VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.
Shugay M, Bagaev DV, Zvyagin IV, Vroomans RM, Crawford JC, Dolton G, Komech EA, Sycheva AL, Koneva AE, Egorov ES, Eliseev AV, Van Dyk E, Dash P, Attaf M, Rius C, Ladell K, McLaren JE, Matthews KK, Clemens EB, Douek DC, Luciani F, van Baarle D, Kedzierska K, Kesmir C, Thomas PG, Price DA, Sewell AK, Chudakov DM. Shugay M, et al. Among authors: crawford jc. Nucleic Acids Res. 2018 Jan 4;46(D1):D419-D427. doi: 10.1093/nar/gkx760. Nucleic Acids Res. 2018. PMID: 28977646 Free PMC article.
Hitting the Target: How T Cells Detect and Eliminate Tumors.
Zamora AE, Crawford JC, Thomas PG. Zamora AE, et al. Among authors: crawford jc. J Immunol. 2018 Jan 15;200(2):392-399. doi: 10.4049/jimmunol.1701413. J Immunol. 2018. PMID: 29311380 Free PMC article. Review.
Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.
Wang Z, Zhu L, Nguyen THO, Wan Y, Sant S, Quiñones-Parra SM, Crawford JC, Eltahla AA, Rizzetto S, Bull RA, Qiu C, Koutsakos M, Clemens EB, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw JM, La Gruta NL, Turner SJ, Cheng AC, Luciani F, Zhang X, Doherty PC, Thomas PG, Xu J, Kedzierska K. Wang Z, et al. Among authors: crawford jc. Nat Commun. 2018 Feb 26;9(1):824. doi: 10.1038/s41467-018-03243-7. Nat Commun. 2018. PMID: 29483513 Free PMC article.
LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.
Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, Green DR. Cunha LD, et al. Among authors: crawford jc. Cell. 2018 Oct 4;175(2):429-441.e16. doi: 10.1016/j.cell.2018.08.061. Epub 2018 Sep 20. Cell. 2018. PMID: 30245008 Free PMC article.
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses.
Koutsakos M, Illing PT, Nguyen THO, Mifsud NA, Crawford JC, Rizzetto S, Eltahla AA, Clemens EB, Sant S, Chua BY, Wong CY, Allen EK, Teng D, Dash P, Boyd DF, Grzelak L, Zeng W, Hurt AC, Barr I, Rockman S, Jackson DC, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Wakim LM, Rossjohn J, Vijaykrishna D, Luciani F, Thomas PG, Gras S, Purcell AW, Kedzierska K. Koutsakos M, et al. Among authors: crawford jc. Nat Immunol. 2019 May;20(5):613-625. doi: 10.1038/s41590-019-0320-6. Epub 2019 Feb 18. Nat Immunol. 2019. PMID: 30778243
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG. Zamora AE, et al. Among authors: crawford jc. Sci Transl Med. 2019 Jun 26;11(498):eaat8549. doi: 10.1126/scitranslmed.aat8549. Sci Transl Med. 2019. PMID: 31243155 Free PMC article.
92 results