Mills GB - Search Results

1

A functional genomic approach to actionable gene fusions for precision oncology.

Li J, Lu H, Ng PK, Pantazi A, Ip CKM, Jeong KJ, Amador B, Tran R, Tsang YH, Yang L, Song X, Dogruluk T, Ren X, Hadjipanayis A, Bristow CA, Lee S, Kucherlapati M, Parfenov M, Tang J, Seth S, Mahadeshwar HS, Mojumdar K, Zeng D, Zhang J, Protopopov A, Seidman JG, Creighton CJ, Lu Y, Sahni N, Shaw KR, Meric-Bernstam F, Futreal A, Chin L, Scott KL, Kucherlapati R, Mills GB, Liang H. Li J, et al. Among authors: mills gb. Sci Adv. 2022 Feb 11;8(6):eabm2382. doi: 10.1126/sciadv.abm2382. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138907 Free PMC article.

2

SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity.

Cuevas B, Lu Y, Watt S, Kumar R, Zhang J, Siminovitch KA, Mills GB. Cuevas B, et al. Among authors: mills gb. J Biol Chem. 1999 Sep 24;274(39):27583-9. doi: 10.1074/jbc.274.39.27583. J Biol Chem. 1999. PMID: 10488096 Free article.

3

Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase.

Cuevas BD, Lu Y, Mao M, Zhang J, LaPushin R, Siminovitch K, Mills GB. Cuevas BD, et al. Among authors: mills gb. J Biol Chem. 2001 Jul 20;276(29):27455-61. doi: 10.1074/jbc.M100556200. Epub 2001 May 3. J Biol Chem. 2001. PMID: 11337495 Free article.

4

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.

Mills GB, Lu Y, Kohn EC. Mills GB, et al. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10031-3. doi: 10.1073/pnas.191379498. Proc Natl Acad Sci U S A. 2001. PMID: 11526226 Free PMC article. No abstract available.

5

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.

Fang X, Yu S, Tanyi JL, Lu Y, Woodgett JR, Mills GB. Fang X, et al. Among authors: mills gb. Mol Cell Biol. 2002 Apr;22(7):2099-110. doi: 10.1128/MCB.22.7.2099-2110.2002. Mol Cell Biol. 2002. PMID: 11884598 Free PMC article.

6

Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.

Koul D, Jasser SA, Lu Y, Davies MA, Shen R, Shi Y, Mills GB, Yung WK. Koul D, et al. Among authors: mills gb. Oncogene. 2002 Apr 4;21(15):2357-64. doi: 10.1038/sj.onc.1205296. Oncogene. 2002. PMID: 11948419

7

Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.

Cui X, Zhang P, Deng W, Oesterreich S, Lu Y, Mills GB, Lee AV. Cui X, et al. Among authors: mills gb. Mol Endocrinol. 2003 Apr;17(4):575-88. doi: 10.1210/me.2002-0318. Epub 2003 Jan 2. Mol Endocrinol. 2003. PMID: 12554765

8

Linking molecular diagnostics to molecular therapeutics: targeting the PI3K pathway in breast cancer.

Mills GB, Kohn E, Lu Y, Eder A, Fang X, Wang H, Bast RC, Gray J, Jaffe R, Hortobagyi G. Mills GB, et al. Semin Oncol. 2003 Oct;30(5 Suppl 16):93-104. doi: 10.1053/j.seminoncol.2003.08.011. Semin Oncol. 2003. PMID: 14613030 Review.

9

Targeting PI3K-AKT pathway for cancer therapy.

Lu Y, Wang H, Mills GB. Lu Y, et al. Among authors: mills gb. Rev Clin Exp Hematol. 2003 Jun;7(2):205-28. Rev Clin Exp Hematol. 2003. PMID: 14763163 Review.

10

Molecular therapeutics: promise and challenges.

Kohn EC, Lu Y, Wang H, Yu Q, Yu S, Hall H, Smith DL, Meric-Bernstam F, Hortobagyi GN, Mills GB. Kohn EC, et al. Among authors: mills gb. Semin Oncol. 2004 Feb;31(1 Suppl 3):39-53. doi: 10.1053/j.seminoncol.2004.01.009. Semin Oncol. 2004. PMID: 15052542 Review.

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