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732 results

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Page 1
Deep imaging flow cytometry.
Huang K, Matsumura H, Zhao Y, Herbig M, Yuan D, Mineharu Y, Harmon J, Findinier J, Yamagishi M, Ohnuki S, Nitta N, Grossman AR, Ohya Y, Mikami H, Isozaki A, Goda K. Huang K, et al. Among authors: harmon j. Lab Chip. 2022 Mar 1;22(5):876-889. doi: 10.1039/d1lc01043c. Lab Chip. 2022. PMID: 35142325
AI on a chip.
Isozaki A, Harmon J, Zhou Y, Li S, Nakagawa Y, Hayashi M, Mikami H, Lei C, Goda K. Isozaki A, et al. Among authors: harmon j. Lab Chip. 2020 Aug 26;20(17):3074-3090. doi: 10.1039/d0lc00521e. Lab Chip. 2020. PMID: 32644061 Review.
Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19.
Nishikawa M, Kanno H, Zhou Y, Xiao TH, Suzuki T, Ibayashi Y, Harmon J, Takizawa S, Hiramatsu K, Nitta N, Kameyama R, Peterson W, Takiguchi J, Shifat-E-Rabbi M, Zhuang Y, Yin X, Rubaiyat AHM, Deng Y, Zhang H, Miyata S, Rohde GK, Iwasaki W, Yatomi Y, Goda K. Nishikawa M, et al. Among authors: harmon j. Nat Commun. 2021 Dec 9;12(1):7135. doi: 10.1038/s41467-021-27378-2. Nat Commun. 2021. PMID: 34887400 Free PMC article.
Platelet activation by thrombin in the absence of the high-affinity thrombin receptor.
Harmon JT, Jamieson GA. Harmon JT, et al. Biochemistry. 1988 Mar 22;27(6):2151-7. doi: 10.1021/bi00406a050. Biochemistry. 1988. PMID: 2837284
High-affinity binding was lost under these conditions, but the platelets continued to show moderate-affinity binding (Kd1 = 16 +/- 5 nM; 930 +/- 300 sites/platelet) and low-affinity binding (Kd2 = 4.6 +/- 3 microM; 170,000 +/- 90,000 sites/platelet), in good agreement with the va …
High-affinity binding was lost under these conditions, but the platelets continued to show moderate-affinity binding (Kd1 = 16 +/- 5 nM; 930 …
Activation of platelets by alpha-thrombin is a receptor-mediated event. D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone-thrombin, but not N alpha-tosyl-L-lysine chloromethyl ketone-thrombin, binds to the high affinity thrombin receptor.
Harmon JT, Jamieson GA. Harmon JT, et al. J Biol Chem. 1986 Dec 5;261(34):15928-33. J Biol Chem. 1986. PMID: 3023333 Free article.
Competition binding studies have been carried out to evaluate the antagonism of TLCK-thrombin (N alpha-tosyl-L-lysine chloromethyl ketone-treated thrombin) and PPACK-thrombin (D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone-treated thrombin) with alpha-thrombin using compu …
Competition binding studies have been carried out to evaluate the antagonism of TLCK-thrombin (N alpha-tosyl-L-lysine chloromethyl ketone-tr …
732 results