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Combined Inhibition of G9a and EZH2 Suppresses Tumor Growth via Synergistic Induction of IL24-Mediated Apoptosis.
Cancer Res. 2022 Apr 1;82(7):1208-1221. doi: 10.1158/0008-5472.CAN-21-2218.
Cancer Res. 2022.
PMID: 35149587
G9a Inhibition Enhances Checkpoint Inhibitor Blockade Response in Melanoma.
Kelly GM, Al-Ejeh F, McCuaig R, Casciello F, Ahmad Kamal N, Ferguson B, Pritchard AL, Ali S, Silva IP, Wilmott JS, Long GV, Scolyer RA, Rao S, Hayward NK, Gannon F, Lee JS.
Kelly GM, et al. Among authors: casciello f.
Clin Cancer Res. 2021 May 1;27(9):2624-2635. doi: 10.1158/1078-0432.CCR-20-3463. Epub 2021 Feb 15.
Clin Cancer Res. 2021.
PMID: 33589432
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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome.
Casciello F, Al-Ejeh F, Miranda M, Kelly G, Baxter E, Windloch K, Gannon F, Lee JS.
Casciello F, et al.
Theranostics. 2020 Mar 15;10(10):4515-4529. doi: 10.7150/thno.41453. eCollection 2020.
Theranostics. 2020.
PMID: 32292512
Free PMC article.
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Functional Role of G9a Histone Methyltransferase in Cancer.
Casciello F, Windloch K, Gannon F, Lee JS.
Casciello F, et al.
Front Immunol. 2015 Sep 25;6:487. doi: 10.3389/fimmu.2015.00487. eCollection 2015.
Front Immunol. 2015.
PMID: 26441991
Free PMC article.
Review.
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G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.
Casciello F, Al-Ejeh F, Kelly G, Brennan DJ, Ngiow SF, Young A, Stoll T, Windloch K, Hill MM, Smyth MJ, Gannon F, Lee JS.
Casciello F, et al.
Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7077-7082. doi: 10.1073/pnas.1618706114. Epub 2017 Jun 19.
Proc Natl Acad Sci U S A. 2017.
PMID: 28630300
Free PMC article.
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G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation.
Casciello F, Lee JS.
Casciello F, et al.
Cell Cycle. 2017;16(21):2001-2002. doi: 10.1080/15384101.2017.1377505. Epub 2017 Oct 3.
Cell Cycle. 2017.
PMID: 28956686
Free PMC article.
No abstract available.
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The anticancer effect of chaetocin is enhanced by inhibition of autophagy.
Jung HJ, Seo I, Casciello F, Jacquelin S, Lane SW, Suh SI, Suh MH, Lee JS, Baek WK.
Jung HJ, et al. Among authors: casciello f.
Cell Death Dis. 2016 Feb 18;7(2):e2098. doi: 10.1038/cddis.2016.15.
Cell Death Dis. 2016.
PMID: 26890137
Free PMC article.
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CRISPR-Cas13d screens identify KILR, a breast cancer risk-associated lncRNA that regulates DNA replication and repair.
Wang L, Bitar M, Lu X, Jacquelin S, Nair S, Sivakumaran H, Hillman KM, Kaufmann S, Ziegman R, Casciello F, Gowda H, Rosenbluh J, Edwards SL, French JD.
Wang L, et al. Among authors: casciello f.
Mol Cancer. 2024 May 15;23(1):101. doi: 10.1186/s12943-024-02021-y.
Mol Cancer. 2024.
PMID: 38745269
Free PMC article.
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