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Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.
Ottilie S, Luth MR, Hellemann E, Goldgof GM, Vigil E, Kumar P, Cheung AL, Song M, Godinez-Macias KP, Carolino K, Yang J, Lopez G, Abraham M, Tarsio M, LeBlanc E, Whitesell L, Schenken J, Gunawan F, Patel R, Smith J, Love MS, Williams RM, McNamara CW, Gerwick WH, Ideker T, Suzuki Y, Wirth DF, Lukens AK, Kane PM, Cowen LE, Durrant JD, Winzeler EA. Ottilie S, et al. Among authors: suzuki y. Commun Biol. 2022 Feb 11;5(1):128. doi: 10.1038/s42003-022-03076-7. Commun Biol. 2022. PMID: 35149760 Free PMC article.
Direct transfer of whole genomes from bacteria to yeast.
Karas BJ, Jablanovic J, Sun L, Ma L, Goldgof GM, Stam J, Ramon A, Manary MJ, Winzeler EA, Venter JC, Weyman PD, Gibson DG, Glass JI, Hutchison CA 3rd, Smith HO, Suzuki Y. Karas BJ, et al. Among authors: suzuki y. Nat Methods. 2013 May;10(5):410-2. doi: 10.1038/nmeth.2433. Epub 2013 Mar 31. Nat Methods. 2013. PMID: 23542886 Free PMC article.
Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling.
Suzuki Y, Assad-Garcia N, Kostylev M, Noskov VN, Wise KS, Karas BJ, Stam J, Montague MG, Hanly TJ, Enriquez NJ, Ramon A, Goldgof GM, Richter RA, Vashee S, Chuang RY, Winzeler EA, Hutchison CA 3rd, Gibson DG, Smith HO, Glass JI, Venter JC. Suzuki Y, et al. Genome Res. 2015 Mar;25(3):435-44. doi: 10.1101/gr.182477.114. Epub 2015 Feb 5. Genome Res. 2015. PMID: 25654978 Free PMC article.
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor.
Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Murray R, Prescott M, McNamara CW, Slayman CW, Amaro RE, Suzuki Y, Winzeler EA. Goldgof GM, et al. Among authors: suzuki y. Sci Rep. 2016 Jun 13;6:27806. doi: 10.1038/srep27806. Sci Rep. 2016. PMID: 27291296 Free PMC article.
Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast.
Ottilie S, Goldgof GM, Calvet CM, Jennings GK, LaMonte G, Schenken J, Vigil E, Kumar P, McCall LI, Lopes ES, Gunawan F, Yang J, Suzuki Y, Siqueira-Neto JL, McKerrow JH, Amaro RE, Podust LM, Durrant JD, Winzeler EA. Ottilie S, et al. Among authors: suzuki y. ACS Chem Biol. 2017 Feb 17;12(2):422-434. doi: 10.1021/acschembio.6b01037. Epub 2016 Dec 23. ACS Chem Biol. 2017. PMID: 27977118 Free PMC article.
Systematic exploration of synergistic drug pairs.
Cokol M, Chua HN, Tasan M, Mutlu B, Weinstein ZB, Suzuki Y, Nergiz ME, Costanzo M, Baryshnikova A, Giaever G, Nislow C, Myers CL, Andrews BJ, Boone C, Roth FP. Cokol M, et al. Among authors: suzuki y. Mol Syst Biol. 2011 Nov 8;7:544. doi: 10.1038/msb.2011.71. Mol Syst Biol. 2011. PMID: 22068327 Free PMC article.
Assembly of large, high G+C bacterial DNA fragments in yeast.
Noskov VN, Karas BJ, Young L, Chuang RY, Gibson DG, Lin YC, Stam J, Yonemoto IT, Suzuki Y, Andrews-Pfannkoch C, Glass JI, Smith HO, Hutchison CA 3rd, Venter JC, Weyman PD. Noskov VN, et al. Among authors: suzuki y. ACS Synth Biol. 2012 Jul 20;1(7):267-73. doi: 10.1021/sb3000194. Epub 2012 May 21. ACS Synth Biol. 2012. PMID: 23651249
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