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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE. Sánchez-Rivera FJ, et al. Among authors: goswami s. Nat Biotechnol. 2022 Jun;40(6):862-873. doi: 10.1038/s41587-021-01172-3. Epub 2022 Feb 14. Nat Biotechnol. 2022. PMID: 35165384 Free PMC article.
Optimized base editors enable efficient editing in cells, organoids and mice.
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Zafra MP, et al. Among authors: goswami s. Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3. Nat Biotechnol. 2018. PMID: 29969439 Free PMC article.
Tankyrase inhibition sensitizes cells to CDK4 blockade.
Foronda M, Tarumoto Y, Schatoff EM, Leach BI, Diaz BJ, Zimmerman J, Goswami S, Shusterman M, Vakoc CR, Dow LE. Foronda M, et al. Among authors: goswami s. PLoS One. 2019 Dec 31;14(12):e0226645. doi: 10.1371/journal.pone.0226645. eCollection 2019. PLoS One. 2019. PMID: 31891587 Free PMC article.
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Han T, Goswami S, Hu Y, Tang F, Zafra MP, Murphy C, Cao Z, Poirier JT, Khurana E, Elemento O, Hechtman JF, Ganesh K, Yaeger R, Dow LE. Han T, et al. Among authors: goswami s. Cancer Discov. 2020 Oct;10(10):1590-1609. doi: 10.1158/2159-8290.CD-19-1536. Epub 2020 Jun 16. Cancer Discov. 2020. PMID: 32546576 Free PMC article.
An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants.
Zafra MP, Parsons MJ, Kim J, Alonso-Curbelo D, Goswami S, Schatoff EM, Han T, Katti A, Fernandez MTC, Wilkinson JE, Piskounova E, Dow LE. Zafra MP, et al. Among authors: goswami s. Cancer Discov. 2020 Nov;10(11):1654-1671. doi: 10.1158/2159-8290.CD-20-0442. Epub 2020 Aug 12. Cancer Discov. 2020. PMID: 32792368 Free PMC article.
Generation of precision preclinical cancer models using regulated in vivo base editing.
Katti A, Vega-Pérez A, Foronda M, Zimmerman J, Zafra MP, Granowsky E, Goswami S, Gardner EE, Diaz BJ, Simon JM, Wuest A, Luan W, Fernandez MTC, Kadina AP, Walker JA 2nd, Holden K, Lowe SW, Sánchez Rivera FJ, Dow LE. Katti A, et al. Among authors: goswami s. Nat Biotechnol. 2024 Mar;42(3):437-447. doi: 10.1038/s41587-023-01900-x. Epub 2023 Aug 10. Nat Biotechnol. 2024. PMID: 37563300
International Survey of Psychosocial Care for Cancer Survivors in Low-/Middle- and High-Income Countries: Current Practices, Barriers, and Facilitators to Care.
Signorelli C, Høeg BL, Asuzu C, Centeno I, Estapé T, Fisher P, Lam W, Levkovich I, Manne S, Miles A, Mullen L, Nekhlyudov L, Sade C, Shaw J, Singleton A, Travado L, Tsuchiya M, Lemmen J, Li J, Jefford M; International Psycho-Oncology Society Survivorship Special Interest Group. Signorelli C, et al. JCO Glob Oncol. 2024 May;10:e2300418. doi: 10.1200/GO.23.00418. JCO Glob Oncol. 2024. PMID: 38781550
1,354 results