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Metabolic determination of cell fate through selective inheritance of mitochondria.
Döhla J, Kuuluvainen E, Gebert N, Amaral A, Englund JI, Gopalakrishnan S, Konovalova S, Nieminen AI, Salminen ES, Torregrosa Muñumer R, Ahlqvist K, Yang Y, Bui H, Otonkoski T, Käkelä R, Hietakangas V, Tyynismaa H, Ori A, Katajisto P. Döhla J, et al. Among authors: kakela r. Nat Cell Biol. 2022 Feb;24(2):148-154. doi: 10.1038/s41556-021-00837-0. Epub 2022 Feb 14. Nat Cell Biol. 2022. PMID: 35165416 Free PMC article.
Coordinated control of adiposity and growth by anti-anabolic kinase ERK7.
Hasygar K, Deniz O, Liu Y, Gullmets J, Hynynen R, Ruhanen H, Kokki K, Käkelä R, Hietakangas V. Hasygar K, et al. Among authors: kakela r. EMBO Rep. 2021 Feb 3;22(2):e49602. doi: 10.15252/embr.201949602. Epub 2020 Dec 28. EMBO Rep. 2021. PMID: 33369866 Free PMC article.
Metabolic gene regulation by Drosophila GATA transcription factor Grain.
Kokki K, Lamichane N, Nieminen AI, Ruhanen H, Morikka J, Robciuc M, Rovenko BM, Havula E, Käkelä R, Hietakangas V. Kokki K, et al. Among authors: kakela r. PLoS Genet. 2021 Oct 11;17(10):e1009855. doi: 10.1371/journal.pgen.1009855. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34634038 Free PMC article.
Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure.
Konovalova S, Torregrosa-Muñumer R, Manjunath P, Liu X, Baral S, Fatima K, Holopainen M, Kvist J, Rajendran J, Yang Y, Varjosalo M, Käkelä R, Somerharju P, Tyynismaa H. Konovalova S, et al. Among authors: kakela r. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2210599120. doi: 10.1073/pnas.2210599120. Epub 2023 Jul 18. Proc Natl Acad Sci U S A. 2023. PMID: 37463214 Free PMC article.
Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells.
Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R, Dalli J, Kerkelä E, Laitinen S. Holopainen M, et al. Among authors: kakela r. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1350-1362. doi: 10.1016/j.bbalip.2019.06.010. Epub 2019 Jun 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31207356
108 results