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Enhanced hepatic clearance of hyposialylated platelets explains thrombocytopenia in GNE-related macrothrombocytopenia.
Noordermeer T, van Asten I, Schutgens REG, Lakerveld AJ, Koekman CA, Hage KY, Sebastian SAE, Huisman A, van den Heuvel DJ, Gerritsen HC, Korporaal SJA, Bierings M, van der Smagt JJ, van Gijn ME, Urbanus RT. Noordermeer T, et al. Among authors: koekman ca. Blood Adv. 2022 Jun 14;6(11):3347-3351. doi: 10.1182/bloodadvances.2021006830. Blood Adv. 2022. PMID: 35255501 Free PMC article. No abstract available.
Insulin inhibits tissue factor expression in monocytes.
Gerrits AJ, Koekman CA, Yildirim C, Nieuwland R, Akkerman JW. Gerrits AJ, et al. Among authors: koekman ca. J Thromb Haemost. 2009 Jan;7(1):198-205. doi: 10.1111/j.1538-7836.2008.03206.x. Epub 2008 Oct 28. J Thromb Haemost. 2009. PMID: 18983503 Free article.
A robust post-insertion method for the preparation of targeted siRNA LNPs.
Swart LE, Koekman CA, Seinen CW, Issa H, Rasouli M, Schiffelers RM, Heidenreich O. Swart LE, et al. Among authors: koekman ca. Int J Pharm. 2022 May 25;620:121741. doi: 10.1016/j.ijpharm.2022.121741. Epub 2022 Apr 11. Int J Pharm. 2022. PMID: 35421533 Free article.
The N-terminal domain of the thermo-regulated surface protein PrpA of Enterococcus faecium binds to fibrinogen, fibronectin and platelets.
Guzmán Prieto AM, Urbanus RT, Zhang X, Bierschenk D, Koekman CA, van Luit-Asbroek M, Ouwerkerk JP, Pape M, Paganelli FL, Wobser D, Huebner J, Hendrickx AP, Bonten MJ, Willems RJ, van Schaik W. Guzmán Prieto AM, et al. Among authors: koekman ca. Sci Rep. 2015 Dec 17;5:18255. doi: 10.1038/srep18255. Sci Rep. 2015. PMID: 26675410 Free PMC article.
Patient autoantibodies induce platelet destruction signals via raft-associated glycoprotein Ibα and Fc RIIa in immune thrombocytopenia.
Urbanus RT, van der Wal DE, Koekman CA, Huisman A, van den Heuvel DJ, Gerritsen HC, Deckmyn H, Akkerman JW, Schutgens RE, Gitz E. Urbanus RT, et al. Among authors: koekman ca. Haematologica. 2013 Jul;98(7):e70-2. doi: 10.3324/haematol.2013.087874. Epub 2013 May 28. Haematologica. 2013. PMID: 23716547 Free PMC article. No abstract available.
15 results