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VhH anti-thrombomodulin clone 1 inhibits TAFI activation and enhances fibrinolysis in human whole blood under flow.
J Thromb Haemost. 2022 May;20(5):1213-1222. doi: 10.1111/jth.15674. Epub 2022 Mar 11.
J Thromb Haemost. 2022.
PMID: 35170225
Free PMC article.
A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry.
van Moorsel MVA, Urbanus RT, Verhoef S, Koekman CA, Vink M, Vermonden T, Maas C, Pasterkamp G, Schiffelers RM.
van Moorsel MVA, et al.
Int J Pharm X. 2019 Jun 21;1:100020. doi: 10.1016/j.ijpx.2019.100020. eCollection 2019 Dec.
Int J Pharm X. 2019.
PMID: 31517285
Free PMC article.
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Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis.
de Maat S, Clark CC, Barendrecht AD, Smits S, van Kleef ND, El Otmani H, Waning M, van Moorsel M, Szardenings M, Delaroque N, Vercruysse K, Urbanus RT, Sebastian S, Lenting PJ, Hagemeyer CE, Renné T, Vanhoorelbeke K, Tersteeg C, Maas C.
de Maat S, et al.
Blood. 2022 Jan 27;139(4):597-607. doi: 10.1182/blood.2021011776.
Blood. 2022.
PMID: 34752601
Free article.
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VWF-targeted thrombolysis to overcome rh-tPA resistance in experimental murine ischemic stroke models.
van Moorsel MVA, de Maat S, Vercruysse K, van Leeuwen EM, Jacqmarcq C, Bonnard T, Vivien D, van der Worp HB, Dijkhuizen RM, Maas C.
van Moorsel MVA, et al.
Blood. 2022 Dec 29;140(26):2844-2848. doi: 10.1182/blood.2022016342.
Blood. 2022.
PMID: 35960811
Free article.
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Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation.
Verhoef JJF, de Groot AM, van Moorsel M, Ritsema J, Beztsinna N, Maas C, Schellekens H.
Verhoef JJF, et al.
Biomaterials. 2017 Mar;119:68-77. doi: 10.1016/j.biomaterials.2016.11.025. Epub 2016 Nov 21.
Biomaterials. 2017.
PMID: 28002754
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Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis.
d'Alessandro E, Becker C, Bergmeier W, Bode C, Bourne JH, Brown H, Buller HR, Ten Cate-Hoek AJ, Ten Cate V, van Cauteren YJM, Cheung YFH, Cleuren A, Coenen D, Crijns HJGM, de Simone I, Dolleman SC, Klein CE, Fernandez DI, Granneman L, van T Hof A, Henke P, Henskens YMC, Huang J, Jennings LK, Jooss N, Karel M, van den Kerkhof D, Klok FA, Kremers B, Lämmle B, Leader A, Lundstrom A, Mackman N, Mannucci PM, Maqsood Z, van der Meijden PEJ, van Moorsel M, Moran LA, Morser J, van Mourik M, Navarro S, Neagoe RAI, Olie RH, van Paridon P, Posma J, Provenzale I, Reitsma PH, Scaf B, Schurgers L, Seelig J, Siegbahn A, Siegerink B, Soehnlein O, Soriano EM, Sowa MA, Spronk HMH, Storey RF, Tantiwong C, Veninga A, Wang X, Watson SP, Weitz J, Zeerleder SS, Ten Cate H; Scientific Reviewer Committee.
d'Alessandro E, et al.
Thromb Haemost. 2020 Apr;120(4):538-564. doi: 10.1055/s-0040-1708035. Epub 2020 Apr 14.
Thromb Haemost. 2020.
PMID: 32289858
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