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CRISPR in cancer biology and therapy.
Katti A, Diaz BJ, Caragine CM, Sanjana NE, Dow LE. Katti A, et al. Among authors: dow le. Nat Rev Cancer. 2022 May;22(5):259-279. doi: 10.1038/s41568-022-00441-w. Epub 2022 Feb 22. Nat Rev Cancer. 2022. PMID: 35194172 Review.
Inducible in vivo genome editing with CRISPR-Cas9.
Dow LE, Fisher J, O'Rourke KP, Muley A, Kastenhuber ER, Livshits G, Tschaharganeh DF, Socci ND, Lowe SW. Dow LE, et al. Nat Biotechnol. 2015 Apr;33(4):390-394. doi: 10.1038/nbt.3155. Epub 2015 Feb 18. Nat Biotechnol. 2015. PMID: 25690852 Free PMC article.
Modeling Disease In Vivo With CRISPR/Cas9.
Dow LE. Dow LE. Trends Mol Med. 2015 Oct;21(10):609-621. doi: 10.1016/j.molmed.2015.07.006. Trends Mol Med. 2015. PMID: 26432018 Free PMC article. Review.
Somatic Genome Editing Goes Viral.
Zafra MP, Dow LE. Zafra MP, et al. Among authors: dow le. Trends Mol Med. 2016 Oct;22(10):831-833. doi: 10.1016/j.molmed.2016.08.004. Epub 2016 Aug 20. Trends Mol Med. 2016. PMID: 27555346 Free PMC article.
Optimized base editors enable efficient editing in cells, organoids and mice.
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Zafra MP, et al. Among authors: dow le. Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3. Nat Biotechnol. 2018. PMID: 29969439 Free PMC article.
CRISPR: Stressed about p53?
Foronda M, Dow LE. Foronda M, et al. Among authors: dow le. Trends Mol Med. 2018 Sep;24(9):731-733. doi: 10.1016/j.molmed.2018.06.010. Epub 2018 Jul 17. Trends Mol Med. 2018. PMID: 30017531
Tankyrase inhibition sensitizes cells to CDK4 blockade.
Foronda M, Tarumoto Y, Schatoff EM, Leach BI, Diaz BJ, Zimmerman J, Goswami S, Shusterman M, Vakoc CR, Dow LE. Foronda M, et al. Among authors: dow le. PLoS One. 2019 Dec 31;14(12):e0226645. doi: 10.1371/journal.pone.0226645. eCollection 2019. PLoS One. 2019. PMID: 31891587 Free PMC article.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
Annunziato S, Lutz C, Henneman L, Bhin J, Wong K, Siteur B, van Gerwen B, de Korte-Grimmerink R, Zafra MP, Schatoff EM, Drenth AP, van der Burg E, Eijkman T, Mukherjee S, Boroviak K, Wessels LF, van de Ven M, Huijbers IJ, Adams DJ, Dow LE, Jonkers J. Annunziato S, et al. Among authors: dow le. EMBO J. 2020 Mar 2;39(5):e102169. doi: 10.15252/embj.2019102169. Epub 2020 Jan 13. EMBO J. 2020. PMID: 31930530 Free PMC article.
86 results