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ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression.
Quek H, Cuní-López C, Stewart R, Colletti T, Notaro A, Nguyen TH, Sun Y, Guo CC, Lupton MK, Roberts TL, Lim YC, Oikari LE, La Bella V, White AR. Quek H, et al. Among authors: stewart r. J Neuroinflammation. 2022 Feb 28;19(1):58. doi: 10.1186/s12974-022-02421-1. J Neuroinflammation. 2022. PMID: 35227277 Free PMC article.
Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery.
Oikari LE, Pandit R, Stewart R, Cuní-López C, Quek H, Sutharsan R, Rantanen LM, Oksanen M, Lehtonen S, de Boer CM, Polo JM, Götz J, Koistinaho J, White AR. Oikari LE, et al. Among authors: stewart r. Stem Cell Reports. 2020 May 12;14(5):924-939. doi: 10.1016/j.stemcr.2020.03.011. Epub 2020 Apr 9. Stem Cell Reports. 2020. PMID: 32275861 Free PMC article.
An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition.
Rantanen LM, Bitar M, Lampinen R, Stewart R, Quek H, Oikari LE, Cunί-Lόpez C, Sutharsan R, Thillaiyampalam G, Iqbal J, Russell D, Penttilä E, Löppönen H, Lehtola JM, Saari T, Hannonen S, Koivisto AM, Haupt LM, Mackay-Sim A, Cristino AS, Kanninen KM, White AR. Rantanen LM, et al. Among authors: stewart r. Cells. 2022 Oct 17;11(20):3258. doi: 10.3390/cells11203258. Cells. 2022. PMID: 36291125 Free PMC article.
A patient-derived olfactory stem cell disease model for ataxia-telangiectasia.
Stewart R, Kozlov S, Matigian N, Wali G, Gatei M, Sutharsan R, Bellette B, Wraith-Kijas A, Cochrane J, Coulthard M, Perry C, Sinclair K, Mackay-Sim A, Lavin MF. Stewart R, et al. Hum Mol Genet. 2013 Jun 15;22(12):2495-509. doi: 10.1093/hmg/ddt101. Epub 2013 Mar 7. Hum Mol Genet. 2013. PMID: 23474819
4,582 results