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Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits.
Pathak GA, Singh K, Wendt FR, Fleming TW, Overstreet C, Koller D, Tylee DS, De Angelis F, Cabrera Mendoza B, Levey DF, Koenen KC, Krystal JH, Pietrzak RH, O' Donell C, Gaziano JM, Falcone G, Stein MB, Gelernter J, Pasaniuc B, Mancuso N, Davis LK, Polimanti R. Pathak GA, et al. Among authors: pasaniuc b. Mol Psychiatry. 2022 Mar;27(3):1394-1404. doi: 10.1038/s41380-022-01488-9. Epub 2022 Mar 3. Mol Psychiatry. 2022. PMID: 35241783 Free PMC article.
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.
Kneppers J, Severson TM, Siefert JC, Schol P, Joosten SEP, Yu IPL, Huang CF, Morova T, Altıntaş UB, Giambartolomei C, Seo JH, Baca SC, Carneiro I, Emberly E, Pasaniuc B, Jerónimo C, Henrique R, Freedman ML, Wessels LFA, Lack NA, Bergman AM, Zwart W. Kneppers J, et al. Among authors: pasaniuc b. Nat Commun. 2022 Nov 30;13(1):7367. doi: 10.1038/s41467-022-35135-2. Nat Commun. 2022. PMID: 36450752 Free PMC article.
Enhanced methods to detect haplotypic effects on gene expression.
Brown R, Kichaev G, Mancuso N, Boocock J, Pasaniuc B. Brown R, et al. Among authors: pasaniuc b. Bioinformatics. 2017 Aug 1;33(15):2307-2313. doi: 10.1093/bioinformatics/btx142. Bioinformatics. 2017. PMID: 28369161 Free PMC article.
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.
Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A; Schizophrenia Working Group of the Psychiatric Genomics Consortium; McCarroll S, Neale BM, Ophoff RA, O'Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. Gusev A, et al. Among authors: pasaniuc b. Nat Genet. 2018 Apr;50(4):538-548. doi: 10.1038/s41588-018-0092-1. Epub 2018 Apr 9. Nat Genet. 2018. PMID: 29632383 Free PMC article.
Probabilistic fine-mapping of transcriptome-wide association studies.
Mancuso N, Freund MK, Johnson R, Shi H, Kichaev G, Gusev A, Pasaniuc B. Mancuso N, et al. Among authors: pasaniuc b. Nat Genet. 2019 Apr;51(4):675-682. doi: 10.1038/s41588-019-0367-1. Epub 2019 Mar 29. Nat Genet. 2019. PMID: 30926970 Free PMC article.
166 results