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EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN. Riggi N, et al. Among authors: aryee mj. Cancer Cell. 2014 Nov 10;26(5):668-681. doi: 10.1016/j.ccell.2014.10.004. Epub 2014 Oct 30. Cancer Cell. 2014. PMID: 25453903 Free PMC article.
EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma.
Möller E, Praz V, Rajendran S, Dong R, Cauderay A, Xing YH, Lee L, Fusco C, Broye LC, Cironi L, Iyer S, Rengarajan S, Awad ME, Naigles B, Letovanec I, Ormas N, Finzi G, La Rosa S, Sessa F, Chebib I, Petur Nielsen G, Digklia A, Spentzos D, Cote GM, Choy E, Aryee M, Stamenkovic I, Boulay G, Rivera MN, Riggi N. Möller E, et al. Nat Commun. 2022 Apr 27;13(1):2267. doi: 10.1038/s41467-022-29910-4. Nat Commun. 2022. PMID: 35477713 Free PMC article.
Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity.
Sanalkumar R, Dong R, Lee L, Xing YH, Iyer S, Letovanec I, La Rosa S, Finzi G, Musolino E, Papait R, Chebib I, Nielsen GP, Renella R, Cote GM, Choy E, Aryee M, Stegmaier K, Stamenkovic I, Rivera MN, Riggi N. Sanalkumar R, et al. Sci Adv. 2023 Mar 31;9(13):eabo3789. doi: 10.1126/sciadv.abo3789. Epub 2023 Mar 31. Sci Adv. 2023. PMID: 37000878 Free PMC article.
Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer.
Desai N, Sajed D, Arora KS, Solovyov A, Rajurkar M, Bledsoe JR, Sil S, Amri R, Tai E, MacKenzie OC, Mino-Kenudson M, Aryee MJ, Ferrone CR, Berger DL, Rivera MN, Greenbaum BD, Deshpande V, Ting DT. Desai N, et al. Among authors: aryee mj. JCI Insight. 2017 Feb 9;2(3):e91078. doi: 10.1172/jci.insight.91078. JCI Insight. 2017. PMID: 28194445 Free PMC article.
105 results