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Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.
Cid MC, Unizony SH, Blockmans D, Brouwer E, Dagna L, Dasgupta B, Hellmich B, Molloy E, Salvarani C, Trapnell BC, Warrington KJ, Wicks I, Samant M, Zhou T, Pupim L, Paolini JF; KPL-301-C001 Investigators. Cid MC, et al. Among authors: wicks i. Ann Rheum Dis. 2022 May;81(5):653-661. doi: 10.1136/annrheumdis-2021-221865. Epub 2022 Mar 9. Ann Rheum Dis. 2022. PMID: 35264321 Free PMC article. Clinical Trial.
Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.
Greven DE, Cohen ES, Gerlag DM, Campbell J, Woods J, Davis N, van Nieuwenhuijze A, Lewis A, Heasmen S, McCourt M, Corkill D, Dodd A, Elvin J, Statache G, Wicks IP, Anderson IK, Nash A, Sleeman MA, Tak PP. Greven DE, et al. Among authors: wicks ip. Ann Rheum Dis. 2015 Oct;74(10):1924-30. doi: 10.1136/annrheumdis-2014-205234. Epub 2014 Jun 16. Ann Rheum Dis. 2015. PMID: 24936585 Free PMC article.
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.
Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL. Moghaddas F, et al. Among authors: wicks ip. Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23. Ann Rheum Dis. 2017. PMID: 28835462 Free PMC article.
NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.
Schlenner S, Pasciuto E, Lagou V, Burton O, Prezzemolo T, Junius S, Roca CP, Seillet C, Louis C, Dooley J, Luong K, Van Nieuwenhove E, Wicks IP, Belz G, Humblet-Baron S, Wouters C, Liston A. Schlenner S, et al. Ann Rheum Dis. 2019 Mar;78(3):342-349. doi: 10.1136/annrheumdis-2018-213764. Epub 2018 Dec 14. Ann Rheum Dis. 2019. PMID: 30552177 Free PMC article.
178 results