Fogh J - Search Results

1

Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.

Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F. Prieto Huarcaya S, et al. Among authors: fogh j. Autophagy. 2022 May;18(5):1127-1151. doi: 10.1080/15548627.2022.2045534. Epub 2022 Apr 28. Autophagy. 2022. PMID: 35287553 Free PMC article.

2

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.

Marques ARA, Di Spiezio A, Thießen N, Schmidt L, Grötzinger J, Lüllmann-Rauch R, Damme M, Storck SE, Pietrzik CU, Fogh J, Bär J, Mikhaylova M, Glatzel M, Bassal M, Bartsch U, Saftig P. Marques ARA, et al. Among authors: fogh j. Autophagy. 2020 May;16(5):811-825. doi: 10.1080/15548627.2019.1637200. Epub 2019 Jul 16. Autophagy. 2020. PMID: 31282275 Free PMC article.

3

Analysis of cathepsin B and cathepsin L treatment to clear toxic lysosomal protein aggregates in neuronal ceroid lipofuscinosis.

Di Spiezio A, Marques ARA, Schmidt L, Thießen N, Gallwitz L, Fogh J, Bartsch U, Saftig P. Di Spiezio A, et al. Among authors: fogh j. Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166205. doi: 10.1016/j.bbadis.2021.166205. Epub 2021 Jun 30. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34214607 Free article.

4

Reversal of peripheral and central neural storage and ataxia after recombinant enzyme replacement therapy in alpha-mannosidosis mice.

Blanz J, Stroobants S, Lüllmann-Rauch R, Morelle W, Lüdemann M, D'Hooge R, Reuterwall H, Michalski JC, Fogh J, Andersson C, Saftig P. Blanz J, et al. Among authors: fogh j. Hum Mol Genet. 2008 Nov 15;17(22):3437-45. doi: 10.1093/hmg/ddn237. Epub 2008 Aug 19. Hum Mol Genet. 2008. PMID: 18713755

5

Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice.

Stroobants S, Damme M, Van der Jeugd A, Vermaercke B, Andersson C, Fogh J, Saftig P, Blanz J, D'Hooge R. Stroobants S, et al. Among authors: fogh j. Neurobiol Dis. 2017 Oct;106:255-268. doi: 10.1016/j.nbd.2017.07.013. Epub 2017 Jul 15. Neurobiol Dis. 2017. PMID: 28720484

6

Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis.

Damme M, Stroobants S, Walkley SU, Lüllmann-Rauch R, D'Hooge R, Fogh J, Saftig P, Lübke T, Blanz J. Damme M, et al. Among authors: fogh j. J Neuropathol Exp Neurol. 2011 Jan;70(1):83-94. doi: 10.1097/NEN.0b013e31820428fa. J Neuropathol Exp Neurol. 2011. PMID: 21157375 Free PMC article.

7

Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis mice.

Damme M, Stroobants S, Lüdemann M, Rothaug M, Lüllmann-Rauch R, Beck HC, Ericsson A, Andersson C, Fogh J, D'Hooge R, Saftig P, Blanz J. Damme M, et al. Among authors: fogh j. Ann Clin Transl Neurol. 2015 Sep 19;2(11):987-1001. doi: 10.1002/acn3.245. eCollection 2015 Nov. Ann Clin Transl Neurol. 2015. PMID: 26817023 Free PMC article.

8

Natural history of alpha mannosidosis a longitudinal study.

Beck M, Olsen KJ, Wraith JE, Zeman J, Michalski JC, Saftig P, Fogh J, Malm D. Beck M, et al. Among authors: fogh j. Orphanet J Rare Dis. 2013 Jun 20;8:88. doi: 10.1186/1750-1172-8-88. Orphanet J Rare Dis. 2013. PMID: 23786919 Free PMC article. Clinical Trial.

9

Efficacy of enzyme replacement therapy in alpha-mannosidosis mice: a preclinical animal study.

Roces DP, Lüllmann-Rauch R, Peng J, Balducci C, Andersson C, Tollersrud O, Fogh J, Orlacchio A, Beccari T, Saftig P, von Figura K. Roces DP, et al. Among authors: fogh j. Hum Mol Genet. 2004 Sep 15;13(18):1979-88. doi: 10.1093/hmg/ddh220. Epub 2004 Jul 21. Hum Mol Genet. 2004. PMID: 15269179

10

Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy.

Matzner U, Herbst E, Hedayati KK, Lüllmann-Rauch R, Wessig C, Schröder S, Eistrup C, Möller C, Fogh J, Gieselmann V. Matzner U, et al. Among authors: fogh j. Hum Mol Genet. 2005 May 1;14(9):1139-52. doi: 10.1093/hmg/ddi126. Epub 2005 Mar 16. Hum Mol Genet. 2005. PMID: 15772092

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