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Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Autophagy. 2022 May;18(5):1127-1151. doi: 10.1080/15548627.2022.2045534. Epub 2022 Apr 28.
Autophagy. 2022.
PMID: 35287553
Free PMC article.
Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.
Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F.
Bunk J, et al. Among authors: prieto huarcaya s.
Front Cell Dev Biol. 2021 Feb 11;9:581805. doi: 10.3389/fcell.2021.581805. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 33681191
Free PMC article.
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Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.
Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F.
Bunk J, et al. Among authors: prieto huarcaya s.
Front Cell Dev Biol. 2021 Jun 23;9:671532. doi: 10.3389/fcell.2021.671532. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 34249927
Free PMC article.
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The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches.
Drobny A, Prieto Huarcaya S, Dobert J, Kluge A, Bunk J, Schlothauer T, Zunke F.
Drobny A, et al. Among authors: prieto huarcaya s.
Biochim Biophys Acta Mol Cell Res. 2022 Jul;1869(7):119243. doi: 10.1016/j.bbamcr.2022.119243. Epub 2022 Feb 23.
Biochim Biophys Acta Mol Cell Res. 2022.
PMID: 35217144
Free article.
Review.
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Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.
Drobny A, Boros FA, Balta D, Prieto Huarcaya S, Caylioglu D, Qazi N, Vandrey J, Schneider Y, Dobert JP, Pitcairn C, Mazzulli JR, Zunke F.
Drobny A, et al. Among authors: prieto huarcaya s.
Transl Neurodegener. 2023 Jun 13;12(1):31. doi: 10.1186/s40035-023-00363-z.
Transl Neurodegener. 2023.
PMID: 37312133
Free PMC article.
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Therapeutic potential of lysosomal cathepsins for neurodegenerative diseases.
Prieto Huarcaya S, Zunke F.
Prieto Huarcaya S, et al.
Neural Regen Res. 2023 Aug;18(8):1713-1714. doi: 10.4103/1673-5374.363181.
Neural Regen Res. 2023.
PMID: 36751788
Free PMC article.
No abstract available.
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