Rose-John S - Search Results

1

Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.

Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F. Prieto Huarcaya S, et al. Autophagy. 2022 May;18(5):1127-1151. doi: 10.1080/15548627.2022.2045534. Epub 2022 Apr 28. Autophagy. 2022. PMID: 35287553 Free PMC article.

2

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.

Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A. Hundhausen C, et al. Blood. 2003 Aug 15;102(4):1186-95. doi: 10.1182/blood-2002-12-3775. Epub 2003 Apr 24. Blood. 2003. PMID: 12714508 Free article.

3

L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth.

Maretzky T, Schulte M, Ludwig A, Rose-John S, Blobel C, Hartmann D, Altevogt P, Saftig P, Reiss K. Maretzky T, et al. Mol Cell Biol. 2005 Oct;25(20):9040-53. doi: 10.1128/MCB.25.20.9040-9053.2005. Mol Cell Biol. 2005. PMID: 16199880 Free PMC article.

4

The shedding protease ADAM17: Physiology and pathophysiology.

Zunke F, Rose-John S. Zunke F, et al. Biochim Biophys Acta Mol Cell Res. 2017 Nov;1864(11 Pt B):2059-2070. doi: 10.1016/j.bbamcr.2017.07.001. Epub 2017 Jul 11. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28705384 Free article. Review.

5

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells.

Cabron AS, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, Dobert JP, Pavlenko E, Schumacher N, Renné T, Taylor PR, Linder S, Rose-John S, Zunke F. Cabron AS, et al. J Immunol. 2018 Nov 15;201(10):3106-3118. doi: 10.4049/jimmunol.1701556. Epub 2018 Oct 24. J Immunol. 2018. PMID: 30355783 Free PMC article.

6

Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation.

Pavlenko E, Cabron AS, Arnold P, Dobert JP, Rose-John S, Zunke F. Pavlenko E, et al. Int J Mol Sci. 2019 May 4;20(9):2198. doi: 10.3390/ijms20092198. Int J Mol Sci. 2019. PMID: 31060243 Free PMC article. Review.

7

Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain.

Dobert JP, Cabron AS, Arnold P, Pavlenko E, Rose-John S, Zunke F. Dobert JP, et al. Biomedicines. 2020 Oct 30;8(11):463. doi: 10.3390/biomedicines8110463. Biomedicines. 2020. PMID: 33143292 Free PMC article.

8

Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F. Bunk J, et al. Front Cell Dev Biol. 2021 Feb 11;9:581805. doi: 10.3389/fcell.2021.581805. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33681191 Free PMC article.

9

Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F. Bunk J, et al. Front Cell Dev Biol. 2021 Jun 23;9:671532. doi: 10.3389/fcell.2021.671532. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34249927 Free PMC article.

10

Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE).

Matthews V, Schuster B, Schütze S, Bussmeyer I, Ludwig A, Hundhausen C, Sadowski T, Saftig P, Hartmann D, Kallen KJ, Rose-John S. Matthews V, et al. J Biol Chem. 2003 Oct 3;278(40):38829-39. doi: 10.1074/jbc.M210584200. Epub 2003 Jun 27. J Biol Chem. 2003. PMID: 12832423 Free article.

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