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Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index.
J Med Chem. 2022 Apr 14;65(7):5593-5605. doi: 10.1021/acs.jmedchem.1c02073. Epub 2022 Mar 17.
J Med Chem. 2022.
PMID: 35298158
Insulin purification-Innovation continuum via synthesis of fundamentals, technology, and modeling.
Roush D, Iammarino M, Chmielowski R, Insaidoo F, McCoy MA, Ortigosa A, Rauscher M.
Roush D, et al.
Biotechnol Bioeng. 2023 May 18. doi: 10.1002/bit.28427. Online ahead of print.
Biotechnol Bioeng. 2023.
PMID: 37200159
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