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Page 1
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose.
Corradin O, Sallari R, Hoang AT, Kassim BS, Ben Hutta G, Cuoto L, Quach BC, Lovrenert K, Hays C, Gryder BE, Iskhakova M, Cates H, Song Y, Bartels CF, Hancock DB, Mash DC, Johnson EO, Akbarian S, Scacheri PC. Corradin O, et al. Among authors: hancock db. Mol Psychiatry. 2022 Apr;27(4):2158-2170. doi: 10.1038/s41380-022-01477-y. Epub 2022 Mar 17. Mol Psychiatry. 2022. PMID: 35301427 Free PMC article.
Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.
Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO. Hancock DB, et al. Mol Psychiatry. 2018 Sep;23(9):1911-1919. doi: 10.1038/mp.2017.193. Epub 2017 Oct 3. Mol Psychiatry. 2018. PMID: 28972577 Free PMC article.
Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome.
Semick SA, Collado-Torres L, Markunas CA, Shin JH, Deep-Soboslay A, Tao R, Huestis MA, Bierut LJ, Maher BS, Johnson EO, Hyde TM, Weinberger DR, Hancock DB, Kleinman JE, Jaffe AE. Semick SA, et al. Among authors: hancock db. Mol Psychiatry. 2020 Dec;25(12):3267-3277. doi: 10.1038/s41380-018-0223-1. Epub 2018 Aug 21. Mol Psychiatry. 2020. PMID: 30131587 Free PMC article.
Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.
Polimanti R, Walters RK, Johnson EC, McClintick JN, Adkins AE, Adkins DE, Bacanu SA, Bierut LJ, Bigdeli TB, Brown S, Bucholz KK, Copeland WE, Costello EJ, Degenhardt L, Farrer LA, Foroud TM, Fox L, Goate AM, Grucza R, Hack LM, Hancock DB, Hartz SM, Heath AC, Hewitt JK, Hopfer CJ, Johnson EO, Kendler KS, Kranzler HR, Krauter K, Lai D, Madden PAF, Martin NG, Maes HH, Nelson EC, Peterson RE, Porjesz B, Riley BP, Saccone N, Stallings M, Wall TL, Webb BT, Wetherill L; Psychiatric Genomics Consortium Substance Use Disorders Workgroup; Edenberg HJ, Agrawal A, Gelernter J. Polimanti R, et al. Among authors: hancock db. Mol Psychiatry. 2020 Aug;25(8):1673-1687. doi: 10.1038/s41380-020-0677-9. Epub 2020 Feb 26. Mol Psychiatry. 2020. PMID: 32099098 Free PMC article.
Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers.
Markunas CA, Semick SA, Quach BC, Tao R, Deep-Soboslay A, Carnes MU, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Jaffe AE, Hancock DB. Markunas CA, et al. Among authors: hancock db. Neuropsychopharmacology. 2021 Feb;46(3):554-560. doi: 10.1038/s41386-020-0782-0. Epub 2020 Jul 30. Neuropsychopharmacology. 2021. PMID: 32731254 Free PMC article.
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.
Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB. Quach BC, et al. Among authors: hancock db. Nat Commun. 2020 Nov 3;11(1):5562. doi: 10.1038/s41467-020-19265-z. Nat Commun. 2020. PMID: 33144568 Free PMC article.
Integration of evidence across human and model organism studies: A meeting report.
Palmer RHC, Johnson EC, Won H, Polimanti R, Kapoor M, Chitre A, Bogue MA, Benca-Bachman CE, Parker CC, Verma A, Reynolds T, Ernst J, Bray M, Kwon SB, Lai D, Quach BC, Gaddis NC, Saba L, Chen H, Hawrylycz M, Zhang S, Zhou Y, Mahaffey S, Fischer C, Sanchez-Roige S, Bandrowski A, Lu Q, Shen L, Philip V, Gelernter J, Bierut LJ, Hancock DB, Edenberg HJ, Johnson EO, Nestler EJ, Barr PB, Prins P, Smith DJ, Akbarian S, Thorgeirsson T, Walton D, Baker E, Jacobson D, Palmer AA, Miles M, Chesler EJ, Emerson J, Agrawal A, Martone M, Williams RW. Palmer RHC, et al. Among authors: hancock db. Genes Brain Behav. 2021 Apr 23;20(6):e12738. doi: 10.1111/gbb.12738. Online ahead of print. Genes Brain Behav. 2021. PMID: 33893716 Free PMC article. Review.
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.
Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H. Sey NYA, et al. Among authors: hancock db. Mol Psychiatry. 2022 Jul;27(7):3085-3094. doi: 10.1038/s41380-022-01558-y. Epub 2022 Apr 14. Mol Psychiatry. 2022. PMID: 35422469 Free PMC article.
97 results