Leppek K - Search Results

1

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.

Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R. Leppek K, et al. Nat Commun. 2022 Mar 22;13(1):1536. doi: 10.1038/s41467-022-28776-w. Nat Commun. 2022. PMID: 35318324 Free PMC article.

2

Functional 5' UTR mRNA structures in eukaryotic translation regulation and how to find them.

Leppek K, Das R, Barna M. Leppek K, et al. Nat Rev Mol Cell Biol. 2018 Mar;19(3):158-174. doi: 10.1038/nrm.2017.103. Epub 2017 Nov 22. Nat Rev Mol Cell Biol. 2018. PMID: 29165424 Free PMC article. Review.

3

Author Correction: Functional 5' UTR mRNA structures in eukaryotic translation regulation and how to find them.

Leppek K, Das R, Barna M. Leppek K, et al. Nat Rev Mol Cell Biol. 2018 Oct;19(10):673. doi: 10.1038/s41580-018-0055-5. Nat Rev Mol Cell Biol. 2018. PMID: 30111874

4

An rRNA variant to deal with stress.

Leppek K, Barna M. Leppek K, et al. Nat Microbiol. 2019 Mar;4(3):382-383. doi: 10.1038/s41564-019-0396-7. Nat Microbiol. 2019. PMID: 30787478 No abstract available.

5

VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide.

Leppek K, Byeon GW, Fujii K, Barna M. Leppek K, et al. Cell Rep. 2021 Jan 19;34(3):108629. doi: 10.1016/j.celrep.2020.108629. Cell Rep. 2021. PMID: 33472078 Free PMC article.

6

The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.

Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M. Simsek D, et al. Among authors: leppek k. Cell. 2017 Jun 1;169(6):1051-1065.e18. doi: 10.1016/j.cell.2017.05.022. Cell. 2017. PMID: 28575669 Free PMC article.

7

Gene- and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments.

Leppek K, Fujii K, Quade N, Susanto TT, Boehringer D, Lenarčič T, Xue S, Genuth NR, Ban N, Barna M. Leppek K, et al. Mol Cell. 2020 Dec 17;80(6):980-995.e13. doi: 10.1016/j.molcel.2020.10.023. Epub 2020 Nov 16. Mol Cell. 2020. PMID: 33202249 Free PMC article.

8

Protein synthesis and translational control: at eye level with the ribosome.

Leppek K, Schott J, Stoecklin G. Leppek K, et al. EMBO Rep. 2011 Dec 1;12(12):1214-6. doi: 10.1038/embor.2011.224. EMBO Rep. 2011. PMID: 22081139 Free PMC article.

9

Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.

Leppek K, Schott J, Reitter S, Poetz F, Hammond MC, Stoecklin G. Leppek K, et al. Cell. 2013 May 9;153(4):869-81. doi: 10.1016/j.cell.2013.04.016. Cell. 2013. PMID: 23663784 Free article.

10

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins.

Leppek K, Stoecklin G. Leppek K, et al. Nucleic Acids Res. 2014 Jan;42(2):e13. doi: 10.1093/nar/gkt956. Epub 2013 Oct 23. Nucleic Acids Res. 2014. PMID: 24157833 Free PMC article.

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