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Unsupervised machine learning for identifying important visual features through bag-of-words using histopathology data from chronic kidney disease.
Lee J, Warner E, Shaikhouni S, Bitzer M, Kretzler M, Gipson D, Pennathur S, Bellovich K, Bhat Z, Gadegbeku C, Massengill S, Perumal K, Saha J, Yang Y, Luo J, Zhang X, Mariani L, Hodgin JB, Rao A; C-PROBE Study. Lee J, et al. Among authors: luo j. Sci Rep. 2022 Mar 22;12(1):4832. doi: 10.1038/s41598-022-08974-8. Sci Rep. 2022. PMID: 35318420 Free PMC article.
MicroRNA-21 in glomerular injury.
Lai JY, Luo J, O'Connor C, Jing X, Nair V, Ju W, Randolph A, Ben-Dov IZ, Matar RN, Briskin D, Zavadil J, Nelson RG, Tuschl T, Brosius FC 3rd, Kretzler M, Bitzer M. Lai JY, et al. Among authors: luo j. J Am Soc Nephrol. 2015 Apr;26(4):805-16. doi: 10.1681/ASN.2013121274. Epub 2014 Aug 21. J Am Soc Nephrol. 2015. PMID: 25145934 Free PMC article. Clinical Trial.
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE). Harder JL, et al. Among authors: luo j. JCI Insight. 2019 Jan 10;4(1):e122697. doi: 10.1172/jci.insight.122697. JCI Insight. 2019. PMID: 30626756 Free PMC article.
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker.
Menon R, Otto EA, Hoover P, Eddy S, Mariani L, Godfrey B, Berthier CC, Eichinger F, Subramanian L, Harder J, Ju W, Nair V, Larkina M, Naik AS, Luo J, Jain S, Sealfon R, Troyanskaya O, Hacohen N, Hodgin JB, Kretzler M, Kpmp KPMP; Nephrotic Syndrome Study Network (NEPTUNE). Menon R, et al. Among authors: luo j. JCI Insight. 2020 Mar 26;5(6):e133267. doi: 10.1172/jci.insight.133267. JCI Insight. 2020. PMID: 32107344 Free PMC article.
SARS-CoV-2 receptor networks in diabetic and COVID-19-associated kidney disease.
Menon R, Otto EA, Sealfon R, Nair V, Wong AK, Theesfeld CL, Chen X, Wang Y, Boppana AS, Luo J, Yang Y, Kasson PM, Schaub JA, Berthier CC, Eddy S, Lienczewski CC, Godfrey B, Dagenais SL, Sohaney R, Hartman J, Fermin D, Subramanian L, Looker HC, Harder JL, Mariani LH, Hodgin JB, Sexton JZ, Wobus CE, Naik AS, Nelson RG, Troyanskaya OG, Kretzler M. Menon R, et al. Among authors: luo j. Kidney Int. 2020 Dec;98(6):1502-1518. doi: 10.1016/j.kint.2020.09.015. Epub 2020 Oct 8. Kidney Int. 2020. PMID: 33038424 Free PMC article.
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. El-Achkar TM, et al. Among authors: luo j. Physiol Genomics. 2021 Jan 1;53(1):1-11. doi: 10.1152/physiolgenomics.00104.2020. Epub 2020 Nov 16. Physiol Genomics. 2021. PMID: 33197228 Free PMC article.
Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis.
Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS; Kidney Precision Medicine Project (KPMP). Schmidt IM, et al. Kidney Int. 2021 Sep;100(3):672-683. doi: 10.1016/j.kint.2021.04.037. Epub 2021 May 27. Kidney Int. 2021. PMID: 34051265 Free PMC article.
Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation.
Menon R, Bomback AS, Lake BB, Stutzke C, Grewenow SM, Menez S, D'Agati VD, Jain S; Kidney Precision Medicine Project. Menon R, et al. Kidney Int. 2022 Jun;101(6):1116-1125. doi: 10.1016/j.kint.2022.03.011. Epub 2022 Mar 23. Kidney Int. 2022. PMID: 35339536 Free PMC article. No abstract available.
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