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Identification and characterisation of sPEPs in Cryptococcus neoformans.
Fungal Genet Biol. 2022 May;160:103688. doi: 10.1016/j.fgb.2022.103688. Epub 2022 Mar 23.
Fungal Genet Biol. 2022.
PMID: 35339703
Broadening the spectrum of fluorescent protein tools for use in the encapsulated human fungal pathogen Cryptococcus neoformans.
Spencer GWK, Chua SMH, Erpf PE, Wizrah MSI, Dyba TG, Condon ND, Fraser JA.
Spencer GWK, et al. Among authors: chua smh.
Fungal Genet Biol. 2020 May;138:103365. doi: 10.1016/j.fgb.2020.103365. Epub 2020 Mar 4.
Fungal Genet Biol. 2020.
PMID: 32145317
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Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans.
Arras SD, Chua SM, Wizrah MS, Faint JA, Yap AS, Fraser JA.
Arras SD, et al.
PLoS One. 2016 Oct 6;11(10):e0164322. doi: 10.1371/journal.pone.0164322. eCollection 2016.
PLoS One. 2016.
PMID: 27711143
Free PMC article.
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Surveying purine biosynthesis across the domains of life unveils promising drug targets in pathogens.
Chua SM, Fraser JA.
Chua SM, et al.
Immunol Cell Biol. 2020 Nov;98(10):819-831. doi: 10.1111/imcb.12389. Epub 2020 Sep 16.
Immunol Cell Biol. 2020.
PMID: 32748425
Review.
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Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
Chua SMH, Wizrah MSI, Luo Z, Lim BYJ, Kappler U, Kobe B, Fraser JA.
Chua SMH, et al.
J Biol Chem. 2021 Oct;297(4):101091. doi: 10.1016/j.jbc.2021.101091. Epub 2021 Aug 17.
J Biol Chem. 2021.
PMID: 34416230
Free PMC article.
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Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.
Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW.
Garcia MD, et al. Among authors: chua smh.
Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9649-E9658. doi: 10.1073/pnas.1809422115. Epub 2018 Sep 24.
Proc Natl Acad Sci U S A. 2018.
PMID: 30249642
Free PMC article.
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AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
Wizrah MSI, Chua SMH, Luo Z, Manik MK, Pan M, Whyte JML, Robertson AAB, Kappler U, Kobe B, Fraser JA.
Wizrah MSI, et al. Among authors: chua smh.
J Biol Chem. 2022 Oct;298(10):102453. doi: 10.1016/j.jbc.2022.102453. Epub 2022 Sep 5.
J Biol Chem. 2022.
PMID: 36063996
Free PMC article.
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Automated intermittent epidural boluses improve analgesia induced by intrathecal fentanyl during labour.
Chua SM, Sia AT.
Chua SM, et al.
Can J Anaesth. 2004 Jun-Jul;51(6):581-5. doi: 10.1007/BF03018402.
Can J Anaesth. 2004.
PMID: 15197122
Clinical Trial.
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