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Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib.
Vigoda M, Mathieson C, Evans N, Hale C, Jennings J, Lucero O, Jeng S, Bottomly D, Clayburgh D, Andersen P, Li R, Petrisor D, Tyner JW, McWeeney S, Kulesz-Martin M. Vigoda M, et al. Among authors: tyner jw. Cancer Biol Ther. 2022 Dec 31;23(1):310-318. doi: 10.1080/15384047.2022.2055420. Cancer Biol Ther. 2022. PMID: 35343367 Free PMC article.
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
Maxson JE, Gotlib J, Pollyea DA, Fleischman AG, Agarwal A, Eide CA, Bottomly D, Wilmot B, McWeeney SK, Tognon CE, Pond JB, Collins RH, Goueli B, Oh ST, Deininger MW, Chang BH, Loriaux MM, Druker BJ, Tyner JW. Maxson JE, et al. Among authors: tyner jw. N Engl J Med. 2013 May 9;368(19):1781-90. doi: 10.1056/NEJMoa1214514. N Engl J Med. 2013. PMID: 23656643 Free PMC article.
Corepressor Rcor1 is essential for murine erythropoiesis.
Yao H, Goldman DC, Nechiporuk T, Kawane S, McWeeney SK, Tyner JW, Fan G, Kerenyi MA, Orkin SH, Fleming WH, Mandel G. Yao H, et al. Among authors: tyner jw. Blood. 2014 May 15;123(20):3175-84. doi: 10.1182/blood-2013-11-538678. Epub 2014 Mar 20. Blood. 2014. PMID: 24652990 Free PMC article.
Therapeutically Targetable ALK Mutations in Leukemia.
Maxson JE, Davare MA, Luty SB, Eide CA, Chang BH, Loriaux MM, Tognon CE, Bottomly D, Wilmot B, McWeeney SK, Druker BJ, Tyner JW. Maxson JE, et al. Among authors: tyner jw. Cancer Res. 2015 Jun 1;75(11):2146-50. doi: 10.1158/0008-5472.CAN-14-1576. Cancer Res. 2015. PMID: 26032424 Free PMC article.
Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
Maxson JE, Abel ML, Wang J, Deng X, Reckel S, Luty SB, Sun H, Gorenstein J, Hughes SB, Bottomly D, Wilmot B, McWeeney SK, Radich J, Hantschel O, Middleton RE, Gray NS, Druker BJ, Tyner JW. Maxson JE, et al. Among authors: tyner jw. Cancer Res. 2016 Jan 1;76(1):127-38. doi: 10.1158/0008-5472.CAN-15-0817. Epub 2015 Dec 17. Cancer Res. 2016. PMID: 26677978 Free PMC article.
Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia.
Richard NP, Pippa R, Cleary MM, Puri A, Tibbitts D, Mahmood S, Christensen DJ, Jeng S, McWeeney S, Look AT, Chang BH, Tyner JW, Vitek MP, Odero MD, Sears R, Agarwal A. Richard NP, et al. Among authors: tyner jw. Oncotarget. 2016 Dec 20;7(51):84214-84227. doi: 10.18632/oncotarget.12394. Oncotarget. 2016. PMID: 27705940 Free PMC article.
217 results