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Multi-modality machine learning predicting Parkinson's disease.
Makarious MB, Leonard HL, Vitale D, Iwaki H, Sargent L, Dadu A, Violich I, Hutchins E, Saffo D, Bandres-Ciga S, Kim JJ, Song Y, Maleknia M, Bookman M, Nojopranoto W, Campbell RH, Hashemi SH, Botia JA, Carter JF, Craig DW, Van Keuren-Jensen K, Morris HR, Hardy JA, Blauwendraat C, Singleton AB, Faghri F, Nalls MA. Makarious MB, et al. Among authors: hutchins e. NPJ Parkinsons Dis. 2022 Apr 1;8(1):35. doi: 10.1038/s41531-022-00288-w. NPJ Parkinsons Dis. 2022. PMID: 35365675 Free PMC article.
The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism.
Bressan E, Reed X, Bansal V, Hutchins E, Cobb MM, Webb MG, Alsop E, Grenn FP, Illarionova A, Savytska N, Violich I, Broeer S, Fernandes N, Sivakumar R, Beilina A, Billingsley KJ, Berghausen J, Pantazis CB, Pitz V, Patel D, Daida K, Meechoovet B, Reiman R, Courtright-Lim A, Logemann A, Antone J, Barch M, Kitchen R, Li Y, Dalgard CL; American Genome Center; Rizzu P, Hernandez DG, Hjelm BE, Nalls M, Gibbs JR, Finkbeiner S, Cookson MR, Van Keuren-Jensen K, Craig DW, Singleton AB, Heutink P, Blauwendraat C. Bressan E, et al. Among authors: hutchins e. Cell Genom. 2023 Feb 6;3(3):100261. doi: 10.1016/j.xgen.2023.100261. eCollection 2023 Mar 8. Cell Genom. 2023. PMID: 36950378 Free PMC article.
RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson's disease.
Craig DW, Hutchins E, Violich I, Alsop E, Gibbs JR, Levy S, Robison M, Prasad N, Foroud T, Crawford KL, Toga AW, Whitsett TG, Kim S, Casey B, Reimer A, Hutten SJ, Frasier M, Kern F, Fehlman T, Keller A, Cookson MR, Van Keuren-Jensen K; Parkinson Progression Marker Initiative. Craig DW, et al. Among authors: hutchins e. Nat Aging. 2021 Aug;1(8):734-747. doi: 10.1038/s43587-021-00088-6. Epub 2021 Aug 5. Nat Aging. 2021. PMID: 37117765
Deep sequencing of sncRNAs reveals hallmarks and regulatory modules of the transcriptome during Parkinson's disease progression.
Kern F, Fehlmann T, Violich I, Alsop E, Hutchins E, Kahraman M, Grammes NL, Guimarães P, Backes C, Poston KL, Casey B, Balling R, Geffers L, Krüger R, Galasko D, Mollenhauer B, Meese E, Wyss-Coray T, Craig DW, Van Keuren-Jensen K, Keller A. Kern F, et al. Among authors: hutchins e. Nat Aging. 2021 Mar;1(3):309-322. doi: 10.1038/s43587-021-00042-6. Epub 2021 Mar 15. Nat Aging. 2021. PMID: 37118411
Distinct Plasma Extracellular Vesicle Transcriptomes in Acute Decompensated Heart Failure Subtypes: A Liquid Biopsy Approach.
Gokulnath P, Spanos M, Lehmann HI, Sheng Q, Rodosthenous R, Chaffin M, Varrias D, Chatterjee E, Hutchins E, Li G, Daaboul G, Rana F, Wang AM, Van Keuren-Jensen K, Ellinor PT, Shah R, Das S. Gokulnath P, et al. Among authors: hutchins e. Circulation. 2024 Apr 2;149(14):1147-1149. doi: 10.1161/CIRCULATIONAHA.123.065513. Epub 2024 Apr 1. Circulation. 2024. PMID: 38557125 No abstract available.
Single molecule characterization of individual extracellular vesicles from pancreatic cancer.
Lennon KM, Wakefield DL, Maddox AL, Brehove MS, Willner AN, Garcia-Mansfield K, Meechoovet B, Reiman R, Hutchins E, Miller MM, Goel A, Pirrotte P, Van Keuren-Jensen K, Jovanovic-Talisman T. Lennon KM, et al. Among authors: hutchins e. J Extracell Vesicles. 2019 Nov 4;8(1):1685634. doi: 10.1080/20013078.2019.1685634. eCollection 2019. J Extracell Vesicles. 2019. PMID: 31741725 Free PMC article.
121 results