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A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.
Tukiainen T, Tynkkynen T, Mäkinen VP, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop PH, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M. Tukiainen T, et al. Among authors: tynkkynen t. Biochem Biophys Res Commun. 2008 Oct 24;375(3):356-61. doi: 10.1016/j.bbrc.2008.08.007. Epub 2008 Aug 26. Biochem Biophys Res Commun. 2008. PMID: 18700135
High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis.
Würtz P, Raiko JR, Magnussen CG, Soininen P, Kangas AJ, Tynkkynen T, Thomson R, Laatikainen R, Savolainen MJ, Laurikka J, Kuukasjärvi P, Tarkka M, Karhunen PJ, Jula A, Viikari JS, Kähönen M, Lehtimäki T, Juonala M, Ala-Korpela M, Raitakari OT. Würtz P, et al. Among authors: tynkkynen t. Eur Heart J. 2012 Sep;33(18):2307-16. doi: 10.1093/eurheartj/ehs020. Epub 2012 Mar 26. Eur Heart J. 2012. PMID: 22450427
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.
Würtz P, Wang Q, Kangas AJ, Richmond RC, Skarp J, Tiainen M, Tynkkynen T, Soininen P, Havulinna AS, Kaakinen M, Viikari JS, Savolainen MJ, Kähönen M, Lehtimäki T, Männistö S, Blankenberg S, Zeller T, Laitinen J, Pouta A, Mäntyselkä P, Vanhala M, Elliott P, Pietiläinen KH, Ripatti S, Salomaa V, Raitakari OT, Järvelin MR, Smith GD, Ala-Korpela M. Würtz P, et al. Among authors: tynkkynen t. PLoS Med. 2014 Dec 9;11(12):e1001765. doi: 10.1371/journal.pmed.1001765. eCollection 2014 Dec. PLoS Med. 2014. PMID: 25490400 Free PMC article.
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts.
Würtz P, Havulinna AS, Soininen P, Tynkkynen T, Prieto-Merino D, Tillin T, Ghorbani A, Artati A, Wang Q, Tiainen M, Kangas AJ, Kettunen J, Kaikkonen J, Mikkilä V, Jula A, Kähönen M, Lehtimäki T, Lawlor DA, Gaunt TR, Hughes AD, Sattar N, Illig T, Adamski J, Wang TJ, Perola M, Ripatti S, Vasan RS, Raitakari OT, Gerszten RE, Casas JP, Chaturvedi N, Ala-Korpela M, Salomaa V. Würtz P, et al. Among authors: tynkkynen t. Circulation. 2015 Mar 3;131(9):774-85. doi: 10.1161/CIRCULATIONAHA.114.013116. Epub 2015 Jan 8. Circulation. 2015. PMID: 25573147 Free PMC article.
Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates.
Wang Q, Kangas AJ, Soininen P, Tiainen M, Tynkkynen T, Puukka K, Ruokonen A, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Perola M, Davey Smith G, Raitakari OT, Järvelin MR, Würtz P, Kettunen J, Ala-Korpela M. Wang Q, et al. Among authors: tynkkynen t. Int J Epidemiol. 2015 Apr;44(2):623-37. doi: 10.1093/ije/dyv093. Epub 2015 Jun 6. Int J Epidemiol. 2015. PMID: 26050255
Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase.
Würtz P, Wang Q, Soininen P, Kangas AJ, Fatemifar G, Tynkkynen T, Tiainen M, Perola M, Tillin T, Hughes AD, Mäntyselkä P, Kähönen M, Lehtimäki T, Sattar N, Hingorani AD, Casas JP, Salomaa V, Kivimäki M, Järvelin MR, Davey Smith G, Vanhala M, Lawlor DA, Raitakari OT, Chaturvedi N, Kettunen J, Ala-Korpela M. Würtz P, et al. Among authors: tynkkynen t. J Am Coll Cardiol. 2016 Mar 15;67(10):1200-1210. doi: 10.1016/j.jacc.2015.12.060. J Am Coll Cardiol. 2016. PMID: 26965542 Free PMC article.
25 results