Denning D - Search Results

1

Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.

Gurtan A, Dominy J, Khalid S, Vong L, Caplan S, Currie T, Richards S, Lamarche L, Denning D, Shpektor D, Gurinovich A, Rasheed A, Hameed S, Saeed S, Saleem I, Jalal A, Abbas S, Sultana R, Rasheed SZ, Memon FU, Shah N, Ishaq M, Khera AV, Danesh J, Frossard P, Saleheen D. Gurtan A, et al. Among authors: denning d. PLoS Genet. 2022 Apr 5;18(4):e1010093. doi: 10.1371/journal.pgen.1010093. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35381001 Free PMC article.

2

Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegans.

Denning DP, Hatch V, Horvitz HR. Denning DP, et al. PLoS Genet. 2013;9(3):e1003341. doi: 10.1371/journal.pgen.1003341. Epub 2013 Mar 7. PLoS Genet. 2013. PMID: 23505386 Free PMC article.

3

SPK-1, an SR protein kinase, inhibits programmed cell death in Caenorhabditis elegans.

Galvin BD, Denning DP, Horvitz HR. Galvin BD, et al. Among authors: denning dp. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1998-2003. doi: 10.1073/pnas.1018805108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245325 Free PMC article.

4

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans.

Denning DP, Hatch V, Horvitz HR. Denning DP, et al. Nature. 2012 Aug 9;488(7410):226-30. doi: 10.1038/nature11240. Nature. 2012. PMID: 22801495 Free PMC article.

5

Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.

Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S. Suzuki J, et al. Science. 2013 Jul 26;341(6144):403-6. doi: 10.1126/science.1236758. Epub 2013 Jul 11. Science. 2013. PMID: 23845944 Free article.

6

Replication stress promotes cell elimination by extrusion.

Dwivedi VK, Pardo-Pastor C, Droste R, Kong JN, Tucker N, Denning DP, Rosenblatt J, Horvitz HR. Dwivedi VK, et al. Nature. 2021 May;593(7860):591-596. doi: 10.1038/s41586-021-03526-y. Epub 2021 May 5. Nature. 2021. PMID: 33953402 Free PMC article.

7

Anti-tubulins DEPendably induce apoptosis.

Denning DP, Hirose T. Denning DP, et al. Nat Cell Biol. 2014 Aug;16(8):741-3. doi: 10.1038/ncb3012. Nat Cell Biol. 2014. PMID: 25082198

8

Intramolecular cohesion of coils mediated by phenylalanine--glycine motifs in the natively unfolded domain of a nucleoporin.

Krishnan VV, Lau EY, Yamada J, Denning DP, Patel SS, Colvin ME, Rexach MF. Krishnan VV, et al. PLoS Comput Biol. 2008 Aug 8;4(8):e1000145. doi: 10.1371/journal.pcbi.1000145. PLoS Comput Biol. 2008. PMID: 18688269 Free PMC article.

9

The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein.

Denning DP, Uversky V, Patel SS, Fink AL, Rexach M. Denning DP, et al. J Biol Chem. 2002 Sep 6;277(36):33447-55. doi: 10.1074/jbc.M203499200. Epub 2002 Jun 13. J Biol Chem. 2002. PMID: 12065587 Free article.

10

Rapid evolution exposes the boundaries of domain structure and function in natively unfolded FG nucleoporins.

Denning DP, Rexach MF. Denning DP, et al. Mol Cell Proteomics. 2007 Feb;6(2):272-82. doi: 10.1074/mcp.M600309-MCP200. Epub 2006 Nov 1. Mol Cell Proteomics. 2007. PMID: 17079785 Free article.

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