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Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
Hu X, Qiao D, Kim W, Moll M, Balte PP, Lange LA, Bartz TM, Kumar R, Li X, Yu B, Cade BE, Laurie CA, Sofer T, Ruczinski I, Nickerson DA, Muzny DM, Metcalf GA, Doddapaneni H, Gabriel S, Gupta N, Dugan-Perez S, Cupples LA, Loehr LR, Jain D, Rotter JI, Wilson JG, Psaty BM, Fornage M, Morrison AC, Vasan RS, Washko G, Rich SS, O'Connor GT, Bleecker E, Kaplan RC, Kalhan R, Redline S, Gharib SA, Meyers D, Ortega V, Dupuis J, London SJ, Lappalainen T, Oelsner EC, Silverman EK, Barr RG, Thornton TA, Wheeler HE; TOPMed Lung Working Group; Cho MH, Im HK, Manichaikul A. Hu X, et al. Among authors: li x. Am J Hum Genet. 2022 May 5;109(5):857-870. doi: 10.1016/j.ajhg.2022.03.007. Epub 2022 Apr 5. Am J Hum Genet. 2022. PMID: 35385699 Free PMC article.
Importance of hedgehog interacting protein and other lung function genes in asthma.
Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Peters SP, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2011 Jun;127(6):1457-65. doi: 10.1016/j.jaci.2011.01.056. Epub 2011 Mar 12. J Allergy Clin Immunol. 2011. PMID: 21397937 Free PMC article.
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ; Mexico City Childhood Asthma Study (MCAAS); Gilliland FD; Children's Health Study (CHS) and HARBORS study; Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE); Martinez FD; Childhood Asthma Research and Education (CARE) Network; Weiss ST; Childhood Asthma Management … See abstract for full author list ➔ Torgerson DG, et al. Among authors: li x. Nat Genet. 2011 Jul 31;43(9):887-92. doi: 10.1038/ng.888. Nat Genet. 2011. PMID: 21804549 Free PMC article.
Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Ford JG, Barnes KC, Burchard EG, Howard TD, Bleecker ER, Meyers DA, Cox NJ, Ober C, Nicolae DL. Torgerson DG, et al. Among authors: li x. J Allergy Clin Immunol. 2012 Sep;130(3):622-629.e9. doi: 10.1016/j.jaci.2012.03.045. Epub 2012 May 18. J Allergy Clin Immunol. 2012. PMID: 22607992 Free PMC article.
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
Li X, Ampleford EJ, Howard TD, Moore WC, Torgerson DG, Li H, Busse WW, Castro M, Erzurum SC, Israel E, Nicolae DL, Ober C, Wenzel SE, Hawkins GA, Bleecker ER, Meyers DA. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2012 Oct;130(4):861-8.e7. doi: 10.1016/j.jaci.2012.04.041. Epub 2012 Jun 12. J Allergy Clin Immunol. 2012. PMID: 22694930 Free PMC article.
Genetics of asthma susceptibility and severity.
Slager RE, Hawkins GA, Li X, Postma DS, Meyers DA, Bleecker ER. Slager RE, et al. Among authors: li x. Clin Chest Med. 2012 Sep;33(3):431-43. doi: 10.1016/j.ccm.2012.05.005. Epub 2012 Jul 7. Clin Chest Med. 2012. PMID: 22929093 Free PMC article. Review.
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Li X, et al. Among authors: li h. J Allergy Clin Immunol. 2013 Aug;132(2):313-20.e15. doi: 10.1016/j.jaci.2013.01.051. Epub 2013 Mar 28. J Allergy Clin Immunol. 2013. PMID: 23541324 Free PMC article.
Clinical heterogeneity in the severe asthma research program.
Moore WC, Fitzpatrick AM, Li X, Hastie AT, Li H, Meyers DA, Bleecker ER. Moore WC, et al. Among authors: li x, li h. Ann Am Thorac Soc. 2013 Dec;10 Suppl(Suppl):S118-24. doi: 10.1513/AnnalsATS.201309-307AW. Ann Am Thorac Soc. 2013. PMID: 24313761 Free PMC article.
Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis.
Moore WC, Hastie AT, Li X, Li H, Busse WW, Jarjour NN, Wenzel SE, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Among authors: li x, li h. J Allergy Clin Immunol. 2014 Jun;133(6):1557-63.e5. doi: 10.1016/j.jaci.2013.10.011. Epub 2013 Dec 9. J Allergy Clin Immunol. 2014. PMID: 24332216 Free PMC article.
169,398 results
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