Gastman BR - Search Results

1

IL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion.

Chen X, Zhao J, Herjan T, Hong L, Liao Y, Liu C, Vasu K, Wang H, Thompson A, Fox PL, Gastman BR, Li X, Li X. Chen X, et al. Among authors: gastman br. J Exp Med. 2022 Jun 6;219(6):e20210693. doi: 10.1084/jem.20210693. Epub 2022 Apr 7. J Exp Med. 2022. PMID: 35389431 Free PMC article.

2

Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain.

Demelash A, Pfannenstiel LW, Tannenbaum CS, Li X, Kalady MF, DeVecchio J, Gastman BR. Demelash A, et al. Among authors: gastman br. J Biol Chem. 2015 Sep 4;290(36):21962-75. doi: 10.1074/jbc.M115.663898. Epub 2015 Jul 23. J Biol Chem. 2015. PMID: 26205817 Free PMC article.

3

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.

Wu L, Chen X, Zhao J, Martin B, Zepp JA, Ko JS, Gu C, Cai G, Ouyang W, Sen G, Stark GR, Su B, Vines CM, Tournier C, Hamilton TA, Vidimos A, Gastman B, Liu C, Li X. Wu L, et al. J Exp Med. 2015 Sep 21;212(10):1571-87. doi: 10.1084/jem.20150204. Epub 2015 Sep 7. J Exp Med. 2015. PMID: 26347473 Free PMC article.

4

IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1⁺ stem cells.

Chen X, Cai G, Liu C, Zhao J, Gu C, Wu L, Hamilton TA, Zhang CJ, Ko J, Zhu L, Qin J, Vidimos A, Koyfman S, Gastman BR, Jensen KB, Li X. Chen X, et al. Among authors: gastman br. J Exp Med. 2019 Jan 7;216(1):195-214. doi: 10.1084/jem.20171849. Epub 2018 Dec 21. J Exp Med. 2019. PMID: 30578323 Free PMC article.

5

A Distinctive Lineage-Negative Cell Population Produces IL-17A in Cutaneous Squamous Cell Carcinoma.

Sun L, Ko J, Vidimos A, Koyfman S, Gastman B. Sun L, et al. J Interferon Cytokine Res. 2020 Aug;40(8):418-424. doi: 10.1089/jir.2020.0039. J Interferon Cytokine Res. 2020. PMID: 32813604

6

A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.

Li C, Phoon YP, Karlinsey K, Tian YF, Thapaliya S, Thongkum A, Qu L, Matz AJ, Cameron M, Cameron C, Menoret A, Funchain P, Song JM, Diaz-Montero CM, Tamilselvan B, Golden JB, Cartwright M, Rodriguez A, Bonin C, Vella A, Zhou B, Gastman BR. Li C, et al. Among authors: gastman br. J Exp Med. 2022 Jan 3;219(1):e20202084. doi: 10.1084/jem.20202084. Epub 2021 Nov 22. J Exp Med. 2022. PMID: 34807232 Free PMC article.

7

MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma.

Fu D, Pfannenstiel L, Demelash A, Phoon YP, Mayell C, Cabrera C, Liu C, Zhao J, Dermawan J, Patil D, DeVecchio J, Kalady M, Souers AJ, Phillips DC, Li X, Gastman B. Fu D, et al. Cell Death Dis. 2022 Jan 18;13(1):63. doi: 10.1038/s41419-021-04334-y. Cell Death Dis. 2022. PMID: 35042842 Free PMC article.

8

LRIG1 engages ligand VISTA and impairs tumor-specific CD8⁺ T cell responses.

Ta HM, Roy D, Zhang K, Alban T, Juric I, Dong J, Parthasarathy PB, Patnaik S, Delaney E, Gilmour C, Zakeri A, Shukla N, Rupani A, Phoon YP, Liu C, Avril S, Gastman B, Chan T, Wang LL. Ta HM, et al. Sci Immunol. 2024 May 17;9(95):eadi7418. doi: 10.1126/sciimmunol.adi7418. Epub 2024 May 17. Sci Immunol. 2024. PMID: 38758807

9

Suboptimal Outcomes in Cutaneous Squamous Cell Cancer of the Head and Neck with Nodal Metastases.

Varra V, Woody NM, Reddy C, Joshi NP, Geiger J, Adelstein DJ, Burkey BB, Scharpf J, Prendes B, Lamarre ED, Lorenz R, Gastman B, Manyam BV, Koyfman SA. Varra V, et al. Anticancer Res. 2018 Oct;38(10):5825-5830. doi: 10.21873/anticanres.12923. Anticancer Res. 2018. PMID: 30275206

10

Ex vivo conditioning with IL-12 protects tumor-infiltrating CD8⁺ T cells from negative regulation by local IFN-γ.

Lin L, Rayman P, Pavicic PG Jr, Tannenbaum C, Hamilton T, Montero A, Ko J, Gastman B, Finke J, Ernstoff M, Diaz-Montero CM. Lin L, et al. Cancer Immunol Immunother. 2019 Mar;68(3):395-405. doi: 10.1007/s00262-018-2280-3. Epub 2018 Dec 14. Cancer Immunol Immunother. 2019. PMID: 30552459 Free PMC article.

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