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Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
Nat Commun. 2022 Apr 11;13(1):1935. doi: 10.1038/s41467-022-29342-0.
Nat Commun. 2022.
PMID: 35410325
Free PMC article.
Clinical Trial.
Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma.
Kristensen NP, Heeke C, Tvingsholm SA, Borch A, Draghi A, Crowther MD, Carri I, Munk KK, Holm JS, Bjerregaard AM, Bentzen AK, Marquard AM, Szallasi Z, McGranahan N, Andersen R, Nielsen M, Jönsson GB, Donia M, Svane IM, Hadrup SR.
Kristensen NP, et al. Among authors: munk kk.
J Clin Invest. 2022 Jan 18;132(2):e150535. doi: 10.1172/JCI150535.
J Clin Invest. 2022.
PMID: 34813506
Free PMC article.
Clinical Trial.
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Three doses of BNT162b2 COVID-19 mRNA vaccine establish long-lasting CD8+ T cell immunity in CLL and MDS patients.
Hernandez SPA, Hersby DS, Munk KK, Tamhane T, Trubach D, Tagliamonte M, Buonaguro L, Gang AO, Hadrup SR, Saini SK.
Hernandez SPA, et al. Among authors: munk kk.
Front Immunol. 2023 Jan 10;13:1035344. doi: 10.3389/fimmu.2022.1035344. eCollection 2022.
Front Immunol. 2023.
PMID: 36703960
Free PMC article.
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TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy.
Tvingsholm SA, Frej MS, Rafa VM, Hansen UK, Ormhøj M, Tyron A, Jensen AWP, Kadivar M, Bentzen AK, Munk KK, Aasbjerg GN, Ternander JSH, Heeke C, Tamhane T, Schmess C, Funt SA, Kjeldsen JW, Kverneland AH, Met Ö, Draghi A, Jakobsen SN, Donia M, Marie Svane I, Hadrup SR.
Tvingsholm SA, et al. Among authors: munk kk.
J Immunother Cancer. 2023 Aug;11(8):e006847. doi: 10.1136/jitc-2023-006847.
J Immunother Cancer. 2023.
PMID: 37586765
Free PMC article.
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IMPROVE: a feature model to predict neoepitope immunogenicity through broad-scale validation of T-cell recognition.
Borch A, Carri I, Reynisson B, Alvarez HMG, Munk KK, Montemurro A, Kristensen NP, Tvingsholm SA, Holm JS, Heeke C, Moss KH, Hansen UK, Schaap-Johansen AL, Bagger FO, de Lima VAB, Rohrberg KS, Funt SA, Donia M, Svane IM, Lassen U, Barra C, Nielsen M, Hadrup SR.
Borch A, et al. Among authors: munk kk.
Front Immunol. 2024 Apr 3;15:1360281. doi: 10.3389/fimmu.2024.1360281. eCollection 2024.
Front Immunol. 2024.
PMID: 38633261
Free PMC article.
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