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Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.
Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H. Sey NYA, et al. Among authors: akbarian s. Mol Psychiatry. 2022 Jul;27(7):3085-3094. doi: 10.1038/s41380-022-01558-y. Epub 2022 Apr 14. Mol Psychiatry. 2022. PMID: 35422469 Free PMC article.
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Mitchell AC, Javidfar B, Pothula V, Ibi D, Shen EY, Peter CJ, Bicks LK, Fehr T, Jiang Y, Brennand KJ, Neve RL, Gonzalez-Maeso J, Akbarian S. Mitchell AC, et al. Among authors: akbarian s. Mol Psychiatry. 2018 Jan;23(1):123-132. doi: 10.1038/mp.2016.254. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115742 Free PMC article.
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.
Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE. Bryois J, et al. Among authors: akbarian s. Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038/s41467-018-05379-y. Nat Commun. 2018. PMID: 30087329 Free PMC article.
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE, Roussos P, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: akbarian s. Science. 2018 Dec 14;362(6420):eaat4311. doi: 10.1126/science.aat4311. Science. 2018. PMID: 30545851 Free PMC article.
A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons.
Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, Borrman T, Wiseman J, Bell A, Bannon MJ, Roussos P, Crary JF, Weng Z, Marenco S, Lipska B, Tsankova NM, Huckins L, Jiang Y, Akbarian S. Espeso-Gil S, et al. Among authors: akbarian s. Genome Med. 2020 Feb 19;12(1):19. doi: 10.1186/s13073-020-0715-x. Genome Med. 2020. PMID: 32075678 Free PMC article.
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: akbarian s. Stem Cell Reports. 2021 Mar 9;16(3):505-518. doi: 10.1016/j.stemcr.2021.02.010. Epub 2021 Feb 13. Stem Cell Reports. 2021. PMID: 33636110 Free PMC article.
Integration of evidence across human and model organism studies: A meeting report.
Palmer RHC, Johnson EC, Won H, Polimanti R, Kapoor M, Chitre A, Bogue MA, Benca-Bachman CE, Parker CC, Verma A, Reynolds T, Ernst J, Bray M, Kwon SB, Lai D, Quach BC, Gaddis NC, Saba L, Chen H, Hawrylycz M, Zhang S, Zhou Y, Mahaffey S, Fischer C, Sanchez-Roige S, Bandrowski A, Lu Q, Shen L, Philip V, Gelernter J, Bierut LJ, Hancock DB, Edenberg HJ, Johnson EO, Nestler EJ, Barr PB, Prins P, Smith DJ, Akbarian S, Thorgeirsson T, Walton D, Baker E, Jacobson D, Palmer AA, Miles M, Chesler EJ, Emerson J, Agrawal A, Martone M, Williams RW. Palmer RHC, et al. Among authors: akbarian s. Genes Brain Behav. 2021 Apr 23;20(6):e12738. doi: 10.1111/gbb.12738. Online ahead of print. Genes Brain Behav. 2021. PMID: 33893716 Free PMC article. Review.
278 results