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Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction.
Eur J Med Chem. 2022 Jun 5;236:114343. doi: 10.1016/j.ejmech.2022.114343. Epub 2022 Apr 4.
Eur J Med Chem. 2022.
PMID: 35429911
RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage.
Nugues AL, El Bouazzati H, Hétuin D, Berthon C, Loyens A, Bertrand E, Jouy N, Idziorek T, Quesnel B.
Nugues AL, et al. Among authors: el bouazzati h.
Cell Death Dis. 2014 Aug 21;5(8):e1384. doi: 10.1038/cddis.2014.347.
Cell Death Dis. 2014.
PMID: 25144719
Free PMC article.
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Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy.
Galiègue-Zouitina S, Fu Q, Carton-Latreche C, Poret N, Cheok M, Leprêtre F, Figeac M, Quesnel B, El Bouazzati H, Shelley CS.
Galiègue-Zouitina S, et al. Among authors: el bouazzati h.
EJHaem. 2021 Jan 20;2(2):196-210. doi: 10.1002/jha2.128. eCollection 2021 May.
EJHaem. 2021.
PMID: 35845268
Free PMC article.
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Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors.
Thuru X, Magnez R, El-Bouazzati H, Vergoten G, Quesnel B, Bailly C.
Thuru X, et al. Among authors: el bouazzati h.
Cancers (Basel). 2022 Jul 11;14(14):3368. doi: 10.3390/cancers14143368.
Cancers (Basel). 2022.
PMID: 35884428
Free PMC article.
Review.
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Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties.
Regnault R, Klupsch F, El-Bouazzati H, Magnez R, Le Biannic R, Leleu-Chavain N, Ahouari H, Vezin H, Millet R, Goossens JF, Thuru X, Bailly C.
Regnault R, et al. Among authors: el bouazzati h.
Molecules. 2023 Apr 15;28(8):3491. doi: 10.3390/molecules28083491.
Molecules. 2023.
PMID: 37110727
Free PMC article.
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