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Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction.
Le Biannic R, Magnez R, Klupsch F, Leleu-Chavain N, Thiroux B, Tardy M, El Bouazzati H, Dezitter X, Renault N, Vergoten G, Bailly C, Quesnel B, Thuru X, Millet R. Le Biannic R, et al. Among authors: thuru x. Eur J Med Chem. 2022 Jun 5;236:114343. doi: 10.1016/j.ejmech.2022.114343. Epub 2022 Apr 4. Eur J Med Chem. 2022. PMID: 35429911
Synthesis and biological evaluation of phenstatin metabolites.
Ghinet A, Rigo B, Hénichart JP, Le Broc-Ryckewaert D, Pommery J, Pommery N, Thuru X, Quesnel B, Gautret P. Ghinet A, et al. Among authors: thuru x. Bioorg Med Chem. 2011 Oct 15;19(20):6042-54. doi: 10.1016/j.bmc.2011.08.047. Epub 2011 Aug 27. Bioorg Med Chem. 2011. PMID: 21920767
Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N. Segaoula Z, et al. Among authors: thuru x. J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30. J Med Chem. 2016. PMID: 27538123 Free article.
PD-1/PD-L1 binding studies using microscale thermophoresis.
Magnez R, Thiroux B, Taront S, Segaoula Z, Quesnel B, Thuru X. Magnez R, et al. Among authors: thuru x. Sci Rep. 2017 Dec 15;7(1):17623. doi: 10.1038/s41598-017-17963-1. Sci Rep. 2017. PMID: 29247197 Free PMC article.
Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P. Gibault F, et al. Among authors: thuru x. Cancers (Basel). 2018 May 8;10(5):140. doi: 10.3390/cancers10050140. Cancers (Basel). 2018. PMID: 29738494 Free PMC article.
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis.
Liberelle M, Magnez R, Thuru X, Bencheikh Y, Ravez S, Quenon C, Drucbert AS, Foulon C, Melnyk P, Van Seuningen I, Lebègue N. Liberelle M, et al. Among authors: thuru x. Sci Rep. 2019 Nov 13;9(1):16678. doi: 10.1038/s41598-019-53099-0. Sci Rep. 2019. PMID: 31723153 Free PMC article.
41 results