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In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue.
Li Z, Tuong ZK, Dean I, Willis C, Gaspal F, Fiancette R, Idris S, Kennedy B, Ferdinand JR, Peñalver A, Cabantous M, Murtuza Baker S, Fry JW, Carlesso G, Hammond SA, Dovedi SJ, Hepworth MR, Clatworthy MR, Withers DR. Li Z, et al. Among authors: hepworth mr. J Exp Med. 2022 Jun 6;219(6):e20210749. doi: 10.1084/jem.20210749. Epub 2022 Apr 26. J Exp Med. 2022. PMID: 35472220 Free PMC article.
Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells.
Withers DR, Hepworth MR, Wang X, Mackley EC, Halford EE, Dutton EE, Marriott CL, Brucklacher-Waldert V, Veldhoen M, Kelsen J, Baldassano RN, Sonnenberg GF. Withers DR, et al. Among authors: hepworth mr. Nat Med. 2016 Mar;22(3):319-23. doi: 10.1038/nm.4046. Epub 2016 Feb 15. Nat Med. 2016. PMID: 26878233 Free PMC article.
Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.
Melo-Gonzalez F, Kammoun H, Evren E, Dutton EE, Papadopoulou M, Bradford BM, Tanes C, Fardus-Reid F, Swann JR, Bittinger K, Mabbott NA, Vallance BA, Willinger T, Withers DR, Hepworth MR. Melo-Gonzalez F, et al. Among authors: hepworth mr. J Exp Med. 2019 Apr 1;216(4):728-742. doi: 10.1084/jem.20180871. Epub 2019 Feb 27. J Exp Med. 2019. PMID: 30814299 Free PMC article.
ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.
Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK. Campbell L, et al. Among authors: hepworth mr. J Exp Med. 2019 Dec 2;216(12):2714-2723. doi: 10.1084/jem.20180610. Epub 2019 Oct 3. J Exp Med. 2019. PMID: 31582416 Free PMC article.
ILC killer: Qu'est-ce que c'est?
Withers DR, Hepworth MR. Withers DR, et al. Among authors: hepworth mr. Sci Immunol. 2022 Apr 8;7(70):eabo2159. doi: 10.1126/sciimmunol.abo2159. Epub 2022 Apr 8. Sci Immunol. 2022. PMID: 35394813 Review.
62 results