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TLR7 gain-of-function genetic variation causes human lupus.
Brown GJ, Cañete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI, Bassett K, Shen Q, Burgio G, Zhang Y, Turnbull C, Meng X, Wu P, Cho E, Miosge LA, Andrews TD, Field MA, Tvorogov D, Lopez AF, Babon JJ, López CA, Gónzalez-Murillo Á, Garulo DC, Pascual V, Levy T, Mallack EJ, Calame DG, Lotze T, Lupski JR, Ding H, Ullah TR, Walters GD, Koina ME, Cook MC, Shen N, de Lucas Collantes C, Corry B, Gantier MP, Athanasopoulos V, Vinuesa CG. Brown GJ, et al. Among authors: lopez ca, lopez af. Nature. 2022 May;605(7909):349-356. doi: 10.1038/s41586-022-04642-z. Epub 2022 Apr 27. Nature. 2022. PMID: 35477763 Free PMC article.
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis.
Tvorogov D, Thomas D, Liau NPD, Dottore M, Barry EF, Lathi M, Kan WL, Hercus TR, Stomski F, Hughes TP, Tergaonkar V, Parker MW, Ross DM, Majeti R, Babon JJ, Lopez AF. Tvorogov D, et al. Among authors: lopez af. Sci Adv. 2018 Nov 28;4(11):eaat3834. doi: 10.1126/sciadv.aat3834. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30498775 Free PMC article.
Regulatory roles of IL-10-producing human follicular T cells.
Cañete PF, Sweet RA, Gonzalez-Figueroa P, Papa I, Ohkura N, Bolton H, Roco JA, Cuenca M, Bassett KJ, Sayin I, Barry E, Lopez A, Canaday DH, Meyer-Hermann M, Doglioni C, Fazekas de St Groth B, Sakaguchi S, Cook MC, Vinuesa CG. Cañete PF, et al. J Exp Med. 2019 Aug 5;216(8):1843-1856. doi: 10.1084/jem.20190493. Epub 2019 Jun 17. J Exp Med. 2019. PMID: 31209070 Free PMC article.
Messing with βc: A unique receptor with many goals.
Kan WL, Cheung Tung Shing KS, Nero TL, Hercus TR, Tvorogov D, Parker MW, Lopez AF. Kan WL, et al. Among authors: lopez af. Semin Immunol. 2021 Apr;54:101513. doi: 10.1016/j.smim.2021.101513. Epub 2021 Nov 24. Semin Immunol. 2021. PMID: 34836771 Review.
14-3-3ζ coordinates adipogenesis of visceral fat.
Lim GE, Albrecht T, Piske M, Sarai K, Lee JTC, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD. Lim GE, et al. Among authors: lopez af. Nat Commun. 2015 Jul 29;6:7671. doi: 10.1038/ncomms8671. Nat Commun. 2015. PMID: 26220403 Free PMC article.
237 results