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141 results

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Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells.
Cai T, Gouble A, Black KL, Skwarska A, Naqvi AS, Taylor D, Zhao M, Yuan Q, Sugita M, Zhang Q, Galetto R, Filipe S, Cavazos A, Han L, Kuruvilla V, Ma H, Weng C, Liu CG, Liu X, Konoplev S, Gu J, Tang G, Su X, Al-Atrash G, Ciurea S, Neelapu SS, Lane AA, Kantarjian H, Guzman ML, Pemmaraju N, Smith J, Thomas-Tikhonenko A, Konopleva M. Cai T, et al. Among authors: guzman ml. Nat Commun. 2022 Apr 28;13(1):2228. doi: 10.1038/s41467-022-29669-8. Nat Commun. 2022. PMID: 35484100 Free PMC article.
Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells.
Han L, Qiu P, Zeng Z, Jorgensen JL, Mak DH, Burks JK, Schober W, McQueen TJ, Cortes J, Tanner SD, Roboz GJ, Kantarjian HM, Kornblau SM, Guzman ML, Andreeff M, Konopleva M. Han L, et al. Among authors: guzman ml. Cytometry A. 2015 Apr;87(4):346-56. doi: 10.1002/cyto.a.22628. Epub 2015 Jan 16. Cytometry A. 2015. PMID: 25598437 Free PMC article.
MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.
Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, Lengner CJ, Verma A, Roboz G, Guzman M, Klimek VM, Abdel-Wahab O, Leslie C, Nimer SD, Kharas MG. Taggart J, et al. Nat Commun. 2016 Feb 22;7:10739. doi: 10.1038/ncomms10739. Nat Commun. 2016. PMID: 26898884 Free PMC article.
Selection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia.
Cruz NM, Sugita M, Ewing-Crystal N, Lam L, Galetto R, Gouble A, Smith J, Hassane DC, Roboz GJ, Guzman ML. Cruz NM, et al. Among authors: guzman ml. Leuk Lymphoma. 2018 Apr;59(4):978-982. doi: 10.1080/10428194.2017.1361023. Epub 2017 Aug 10. Leuk Lymphoma. 2018. PMID: 28795850 Free PMC article. No abstract available.
Approaches to Targeting Cancer Stem Cells in Solid Tumors.
Caldas-Lopes E, Gomez-Arteaga A, Guzman ML. Caldas-Lopes E, et al. Among authors: guzman ml. Curr Stem Cell Res Ther. 2019;14(5):421-427. doi: 10.2174/1574888X14666190222164429. Curr Stem Cell Res Ther. 2019. PMID: 30806324 Review.
CD123 as a Therapeutic Target Against Malignant Stem Cells.
Sugita M, Guzman ML. Sugita M, et al. Among authors: guzman ml. Hematol Oncol Clin North Am. 2020 Jun;34(3):553-564. doi: 10.1016/j.hoc.2020.01.004. Epub 2020 Mar 20. Hematol Oncol Clin North Am. 2020. PMID: 32336419 Review.
BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells.
Kawabata KC, Zong H, Meydan C, Wyman S, Wouters BJ, Sugita M, Goswami S, Albert M, Yip W, Roboz GJ, Chen Z, Delwel R, Carroll M, Mason CE, Melnick A, Guzman ML. Kawabata KC, et al. Among authors: guzman ml. Blood. 2021 Feb 11;137(6):812-825. doi: 10.1182/blood.2019001745. Blood. 2021. PMID: 32911532 Free PMC article.
Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia.
Sugita M, Galetto R, Zong H, Ewing-Crystal N, Trujillo-Alonso V, Mencia-Trinchant N, Yip W, Filipe S, Lebuhotel C, Gouble A, Hassane DC, Smith J, Roboz GJ, Guzman ML. Sugita M, et al. Among authors: guzman ml. Nat Commun. 2022 Apr 28;13(1):2227. doi: 10.1038/s41467-022-29668-9. Nat Commun. 2022. PMID: 35484102 Free PMC article.
141 results