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Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
Fass DM, Lewis MC, Ahmad R, Szucs MJ, Zhang Q, Fleishman M, Wang D, Kim MJ, Biag J, Carr SA, Scolnick EM, Premont RT, Haggarty SJ. Fass DM, et al. Among authors: fleishman m. Mol Psychiatry. 2022 Aug;27(8):3272-3285. doi: 10.1038/s41380-022-01557-z. Epub 2022 May 3. Mol Psychiatry. 2022. PMID: 35505090 Free PMC article.
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities.
Madison JM, Zhou F, Nigam A, Hussain A, Barker DD, Nehme R, van der Ven K, Hsu J, Wolf P, Fleishman M, O'Dushlaine C, Rose S, Chambert K, Lau FH, Ahfeldt T, Rueckert EH, Sheridan SD, Fass DM, Nemesh J, Mullen TE, Daheron L, McCarroll S, Sklar P, Perlis RH, Haggarty SJ. Madison JM, et al. Among authors: fleishman m. Mol Psychiatry. 2015 Jun;20(6):703-17. doi: 10.1038/mp.2015.7. Epub 2015 Mar 3. Mol Psychiatry. 2015. PMID: 25733313 Free PMC article.
Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.
Kim MJ, Biag J, Fass DM, Lewis MC, Zhang Q, Fleishman M, Gangwar SP, Machius M, Fromer M, Purcell SM, McCarroll SA, Rudenko G, Premont RT, Scolnick EM, Haggarty SJ. Kim MJ, et al. Among authors: fleishman m. Mol Psychiatry. 2017 Mar;22(3):417-429. doi: 10.1038/mp.2016.98. Epub 2016 Jul 26. Mol Psychiatry. 2017. PMID: 27457813 Free PMC article.
Anterior thalamic circuits crucial for working memory.
Roy DS, Zhang Y, Aida T, Shen C, Skaggs KM, Hou Y, Fleishman M, Mosto O, Weninger A, Feng G. Roy DS, et al. Among authors: fleishman m. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2118712119. doi: 10.1073/pnas.2118712119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537049 Free PMC article.
Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice.
Guo B, Liu T, Choi S, Mao H, Wang W, Xi K, Jones C, Hartley ND, Feng D, Chen Q, Liu Y, Wimmer RD, Xie Y, Zhao N, Ou J, Arias-Garcia MA, Malhotra D, Liu Y, Lee S, Pasqualoni S, Kast RJ, Fleishman M, Halassa MM, Wu S, Fu Z. Guo B, et al. Among authors: fleishman m. Cell Rep Med. 2024 May 21;5(5):101534. doi: 10.1016/j.xcrm.2024.101534. Epub 2024 Apr 25. Cell Rep Med. 2024. PMID: 38670100 Free article.
63 results