Chen J - Search Results

1

Aging Alters the Aortic Proteome in Health and Thoracic Aortic Aneurysm.

Tyrrell DJ, Chen J, Li BY, Wood SC, Rosebury-Smith W, Remmer HA, Jiang L, Zhang M, Salmon M, Ailawadi G, Yang B, Goldstein DR. Tyrrell DJ, et al. Among authors: chen j. Arterioscler Thromb Vasc Biol. 2022 Aug;42(8):1060-1076. doi: 10.1161/ATVBAHA.122.317643. Epub 2022 May 5. Arterioscler Thromb Vasc Biol. 2022. PMID: 35510553 Free PMC article.

2

Influenza virus inoculum volume is critical to elucidate age-dependent mortality in mice.

Smith CA, Kulkarni U, Chen J, Goldstein DR. Smith CA, et al. Among authors: chen j. Aging Cell. 2019 Apr;18(2):e12893. doi: 10.1111/acel.12893. Epub 2019 Jan 11. Aging Cell. 2019. PMID: 30632262 Free PMC article.

3

Role of Aging and the Immune Response to Respiratory Viral Infections: Potential Implications for COVID-19.

Chen J, Kelley WJ, Goldstein DR. Chen J, et al. J Immunol. 2020 Jul 15;205(2):313-320. doi: 10.4049/jimmunol.2000380. Epub 2020 Jun 3. J Immunol. 2020. PMID: 32493812 Free PMC article. Review.

4

PGE₂ accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking.

Penke LR, Speth JM, Draijer C, Zaslona Z, Chen J, Mancuso P, Freeman CM, Curtis JL, Goldstein DR, Peters-Golden M. Penke LR, et al. Among authors: chen j. Life Sci Alliance. 2020 Aug 20;3(11):e202000800. doi: 10.26508/lsa.202000800. Print 2020 Nov. Life Sci Alliance. 2020. PMID: 32820026 Free PMC article.

5

Treating exuberant, non-resolving inflammation in the lung; Implications for acute respiratory distress syndrome and COVID-19.

Gilroy DW, De Maeyer RPH, Tepper M, O'Brien A, Uddin M, Chen J, Goldstein DR, Akbar AN. Gilroy DW, et al. Among authors: chen j. Pharmacol Ther. 2021 May;221:107745. doi: 10.1016/j.pharmthera.2020.107745. Epub 2020 Nov 11. Pharmacol Ther. 2021. PMID: 33188794 Free PMC article. Review.

6

Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice.

Kelley WJ, Wragg KM, Chen J, Murthy T, Xu Q, Boyne MT, Podojil JR, Elhofy A, Goldstein DR. Kelley WJ, et al. Among authors: chen j. JCI Insight. 2022 Aug 8;7(15):e156320. doi: 10.1172/jci.insight.156320. JCI Insight. 2022. PMID: 35737459 Free PMC article.

7

How aging impacts vaccine efficacy: known molecular and cellular mechanisms and future directions.

Chen J, Deng JC, Goldstein DR. Chen J, et al. Trends Mol Med. 2022 Dec;28(12):1100-1111. doi: 10.1016/j.molmed.2022.09.008. Epub 2022 Oct 7. Trends Mol Med. 2022. PMID: 36216643 Free PMC article. Review.

8

Age-induced prostaglandin E₂ impairs mitochondrial fitness and increases mortality to influenza infection.

Chen J, Deng JC, Zemans RL, Bahmed K, Kosmider B, Zhang M, Peters-Golden M, Goldstein DR. Chen J, et al. Nat Commun. 2022 Nov 9;13(1):6759. doi: 10.1038/s41467-022-34593-y. Nat Commun. 2022. PMID: 36351902 Free PMC article.

9

OXPHOS promotes apoptotic resistance and cellular persistence in T_H17 cells in the periphery and tumor microenvironment.

Hong HS, Mbah NE, Shan M, Loesel K, Lin L, Sajjakulnukit P, Correa LO, Andren A, Lin J, Hayashi A, Magnuson B, Chen J, Li Z, Xie Y, Zhang L, Goldstein DR, Carty SA, Lei YL, Opipari AW, Argüello RJ, Kryczek I, Kamada N, Zou W, Franchi L, Lyssiotis CA. Hong HS, et al. Among authors: chen j. Sci Immunol. 2022 Nov 25;7(77):eabm8182. doi: 10.1126/sciimmunol.abm8182. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399539 Free PMC article.

10

Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis.

Song J, Farris D, Ariza P, Moorjani S, Varghese M, Blin M, Chen J, Tyrrell D, Zhang M, Singer K, Salmon M, Goldstein DR. Song J, et al. Among authors: chen j. Aging Cell. 2023 Feb;22(2):e13783. doi: 10.1111/acel.13783. Epub 2023 Jan 23. Aging Cell. 2023. PMID: 36683460 Free PMC article.

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