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CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk.
Baer C, Kimura S, Rana MS, Kleist AB, Flerlage T, Feith DJ, Chockley P, Walter W, Meggendorfer M, Olson TL, Cheon H, Olson KC, Ratan A, Mueller ML, Foran JM, Janke LJ, Qu C, Porter SN, Pruett-Miller SM, Kalathur RC, Haferlach C, Kern W, Paietta E, Thomas PG, Babu MM, Loughran TP Jr, Iacobucci I, Haferlach T, Mullighan CG. Baer C, et al. Among authors: thomas pg. Nat Genet. 2022 May;54(5):637-648. doi: 10.1038/s41588-022-01059-2. Epub 2022 May 5. Nat Genet. 2022. PMID: 35513723 Free PMC article.
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG. Zamora AE, et al. Among authors: thomas pg. Sci Transl Med. 2019 Jun 26;11(498):eaat8549. doi: 10.1126/scitranslmed.aat8549. Sci Transl Med. 2019. PMID: 31243155 Free PMC article.
Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.
Waanders E, Gu Z, Dobson SM, Antić Ž, Crawford JC, Ma X, Edmonson MN, Payne-Turner D, van de Vorst M, Jongmans MCJ, McGuire I, Zhou X, Wang J, Shi L, Pounds S, Pei D, Cheng C, Song G, Fan Y, Shao Y, Rusch M, McCastlain K, Yu J, van Boxtel R, Blokzijl F, Iacobucci I, Roberts KG, Wen J, Wu G, Ma J, Easton J, Neale G, Olsen SR, Nichols KE, Pui CH, Zhang J, Evans WE, Relling MV, Yang JJ, Thomas PG, Dick JE, Kuiper RP, Mullighan CG. Waanders E, et al. Among authors: thomas pg. Blood Cancer Discov. 2020 Jul;1(1):96-111. doi: 10.1158/0008-5472.BCD-19-0041. Blood Cancer Discov. 2020. PMID: 32793890 Free PMC article.
Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL.
Zhao Y, Aldoss I, Qu C, Crawford JC, Gu Z, Allen EK, Zamora AE, Alexander TB, Wang J, Goto H, Imamura T, Akahane K, Marcucci G, Stein AS, Bhatia R, Thomas PG, Forman SJ, Mullighan CG, Roberts KG. Zhao Y, et al. Among authors: thomas pg. Blood. 2021 Jan 28;137(4):471-484. doi: 10.1182/blood.2020006287. Blood. 2021. PMID: 32881995 Free PMC article.
Engineering naturally occurring CD7- T cells for the immunotherapy of hematological malignancies.
Freiwan A, Zoine JT, Crawford JC, Vaidya A, Schattgen SA, Myers JA, Patil SL, Khanlari M, Inaba H, Klco JM, Mullighan CG, Krenciute G, Chockley PJ, Naik S, Langfitt DM, Mamonkin M, Obeng EA, Thomas PG, Gottschalk S, Velasquez MP. Freiwan A, et al. Among authors: thomas pg. Blood. 2022 Dec 22;140(25):2684-2696. doi: 10.1182/blood.2021015020. Blood. 2022. PMID: 35914226 Free PMC article.
Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection.
Cortez V, Livingston B, Sharp B, Hargest V, Papizan JB, Pedicino N, Lanning S, Jordan SV, Gulman J, Vogel P, DuBois RM, Crawford JC, Boyd DF, Pruett-Miller SM, Thomas PG, Schultz-Cherry S. Cortez V, et al. Among authors: thomas pg. Mucosal Immunol. 2023 Aug;16(4):551-562. doi: 10.1016/j.mucimm.2023.05.011. Epub 2023 Jun 7. Mucosal Immunol. 2023. PMID: 37290501 Free PMC article.
363 results