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Page 1
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Drosos Y, Myers JA, Xu B, Mathias KM, Beane EC, Radko-Juettner S, Mobley RJ, Larsen ME, Piccioni F, Ma X, Low J, Hansen BS, Peters ST, Bhanu NV, Dhanda SK, Chen T, Upadhyaya SA, Pruett-Miller SM, Root DE, Garcia BA, Partridge JF, Roberts CWM. Drosos Y, et al. Among authors: upadhyaya sa. Mol Cell. 2022 Jul 7;82(13):2472-2489.e8. doi: 10.1016/j.molcel.2022.04.015. Epub 2022 May 9. Mol Cell. 2022. PMID: 35537449 Free PMC article.
Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials.
Upadhyaya SA, Robinson GW, Onar-Thomas A, Orr BA, Johann P, Wu G, Billups CA, Tatevossian RG, Dhanda SK, Srinivasan A, Broniscer A, Qaddoumi I, Vinitsky A, Armstrong GT, Bendel AE, Hassall T, Partap S, Fisher PG, Crawford JR, Chintagumpala M, Bouffet E, Gururangan S, Mostafavi R, Sanders RP, Klimo P Jr, Patay Z, Indelicato DJ, Nichols KE, Boop FA, Merchant TE, Kool M, Ellison DW, Gajjar A. Upadhyaya SA, et al. Clin Cancer Res. 2021 May 15;27(10):2879-2889. doi: 10.1158/1078-0432.CCR-20-4731. Epub 2021 Mar 18. Clin Cancer Res. 2021. PMID: 33737307 Free PMC article. Clinical Trial.
Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children's Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials.
Liu APY, Dhanda SK, Lin T, Sioson E, Vasilyeva A, Gudenas B, Tatevossian RG, Jia S, Neale G, Bowers DC, Hassall T, Partap S, Crawford JR, Chintagumpala M, Bouffet E, McCowage G, Broniscer A, Qaddoumi I, Armstrong G, Wright KD, Upadhyaya SA, Vinitsky A, Tinkle CL, Lucas J, Chiang J, Indelicato DJ, Sanders R, Klimo P Jr, Boop FA, Merchant TE, Ellison DW, Northcott PA, Orr BA, Zhou X, Onar-Thomas A, Gajjar A, Robinson GW. Liu APY, et al. Among authors: upadhyaya sa. Acta Neuropathol. 2022 Oct;144(4):733-746. doi: 10.1007/s00401-022-02484-7. Epub 2022 Aug 18. Acta Neuropathol. 2022. PMID: 35982322 Free PMC article. Clinical Trial.
High-grade glioma in infants and young children is histologically, molecularly, and clinically diverse: Results from the SJYC07 trial and institutional experience.
Chiang J, Bagchi A, Li X, Dhanda SK, Huang J, Pinto SN, Sioson E, Dalton J, Tatevossian RG, Jia S, Partap S, Fisher PG, Bowers DC, Hassall TEG, Lu C, Zaldivar-Peraza A, Wright KD, Broniscer A, Qaddoumi I, Upadhyaya SA, Vinitsky A, Sabin ND, Orr BA, Klimo P Jr, Boop FA, Ashford JM, Conklin HM, Onar-Thomas A, Zhou X, Ellison DW, Gajjar A, Robinson GW. Chiang J, et al. Among authors: upadhyaya sa. Neuro Oncol. 2024 Jan 5;26(1):178-190. doi: 10.1093/neuonc/noad130. Neuro Oncol. 2024. PMID: 37503880
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
He C, Xu K, Zhu X, Dunphy PS, Gudenas B, Lin W, Twarog N, Hover LD, Kwon CH, Kasper LH, Zhang J, Li X, Dalton J, Jonchere B, Mercer KS, Currier DG, Caufield W, Wang Y, Xie J, Broniscer A, Wetmore C, Upadhyaya SA, Qaddoumi I, Klimo P, Boop F, Gajjar A, Zhang J, Orr BA, Robinson GW, Monje M, Freeman Iii BB, Roussel MF, Northcott PA, Chen T, Rankovic Z, Wu G, Chiang J, Tinkle CL, Shelat AA, Baker SJ. He C, et al. Among authors: upadhyaya sa. Nat Commun. 2021 Jul 2;12(1):4089. doi: 10.1038/s41467-021-24168-8. Nat Commun. 2021. PMID: 34215733 Free PMC article.
Infratentorial C11orf95-fused gliomas share histologic, immunophenotypic, and molecular characteristics of supratentorial RELA-fused ependymoma.
Keenan C, Graham RT, Harreld JH, Lucas JT Jr, Finkelstein D, Wheeler D, Li X, Dalton J, Upadhyaya SA, Raimondi SC, Boop FA, DeCuypere M, Zhang J, Vinitsky A, Wang L, Chiang J. Keenan C, et al. Among authors: upadhyaya sa. Acta Neuropathol. 2020 Dec;140(6):963-965. doi: 10.1007/s00401-020-02238-3. Epub 2020 Oct 24. Acta Neuropathol. 2020. PMID: 33099686 Free PMC article. No abstract available.
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.
Holdhof D, Johann PD, Spohn M, Bockmayr M, Safaei S, Joshi P, Masliah-Planchon J, Ho B, Andrianteranagna M, Bourdeaut F, Huang A, Kool M, Upadhyaya SA, Bendel AE, Indenbirken D, Foulkes WD, Bush JW, Creytens D, Kordes U, Frühwald MC, Hasselblatt M, Schüller U. Holdhof D, et al. Among authors: upadhyaya sa. Acta Neuropathol. 2021 Feb;141(2):291-301. doi: 10.1007/s00401-020-02250-7. Epub 2020 Dec 17. Acta Neuropathol. 2021. PMID: 33331994 Free PMC article.
37 results