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Lung microbiome composition and bronchial epithelial gene expression in patients with COPD versus healthy individuals: a bacterial 16S rRNA gene sequencing and host transcriptomic analysis.
Ramsheh MY, Haldar K, Esteve-Codina A, Purser LF, Richardson M, Müller-Quernheim J, Greulich T, Nowinski A, Barta I, Stendardo M, Boschetto P, Korzybski D, Prasse A, Parr DG, Hohlfeld JM, Döme B, Welte T, Heath S, Gut I, Morrissey JA, Ziegler-Heitbrock L, Barer MR, Singh D, Brightling CE. Ramsheh MY, et al. Among authors: gut i. Lancet Microbe. 2021 Jul;2(7):e300-e310. doi: 10.1016/S2666-5247(21)00035-5. Epub 2021 Apr 23. Lancet Microbe. 2021. PMID: 35544166 Free article.
The EvA study: aims and strategy.
Ziegler-Heitbrock L, Frankenberger M, Heimbeck I, Burggraf D, Wjst M, Häussinger K, Brightling C, Gupta S, Parr D, Subramanian D, Singh D, Kolsum U, Boschetto P, Potena A, Gorecka D, Nowinski A, Barta I, Döme B, Strausz J, Greulich T, Vogelmeier C, Bals R, Hohlfeld JM, Welte T, Venge P, Gut I, Boland A, Olaso R, Hager J, Hiemstra P, Rabe KF, Unmüssig M, Müller-Quernheim J, Prasse A. Ziegler-Heitbrock L, et al. Among authors: gut i. Eur Respir J. 2012 Oct;40(4):823-9. doi: 10.1183/09031936.00142811. Epub 2012 Mar 22. Eur Respir J. 2012. PMID: 22441733 Free article.
Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography.
Subramanian DR, Gupta S, Burggraf D, Vom Silberberg SJ, Heimbeck I, Heiss-Neumann MS, Haeussinger K, Newby C, Hargadon B, Raj V, Singh D, Kolsum U, Hofer TP, Al-Shair K, Luetzen N, Prasse A, Müller-Quernheim J, Benea G, Leprotti S, Boschetto P, Gorecka D, Nowinski A, Oniszh K, Castell WZ, Hagen M, Barta I, Döme B, Strausz J, Greulich T, Vogelmeier C, Koczulla AR, Gut I, Hohlfeld J, Welte T, Lavae-Mokhtari M, Ziegler-Heitbrock L, Brightling C, Parr DG. Subramanian DR, et al. Among authors: gut i. Eur Respir J. 2016 Jul;48(1):92-103. doi: 10.1183/13993003.01878-2015. Epub 2016 May 26. Eur Respir J. 2016. PMID: 27230444 Free article.
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.
George L, Taylor AR, Esteve-Codina A, Soler Artigas M, Thun GA, Bates S, Pavlidis S, Wagers S, Boland A, Prasse A, Boschetto P, Parr DG, Nowinski A, Barta I, Hohlfeld J, Greulich T, van den Berge M, Hiemstra PS, Timens W, Hinks T, Wenzel S, Siddiqui S, Richardson M, Venge P, Heath S, Gut I, Tobin MD, Edwards L, Riley JH, Djukanovic R, Auffray C, De-Meulder B, Erik-Dahlen S, Adcock IM, Chung KF, Ziegler-Heitbrock L, Sterk PJ, Singh D, Brightling CE; U-BIOPRED and the EvA study teams. George L, et al. Among authors: gut i. Allergy. 2020 Feb;75(2):370-380. doi: 10.1111/all.14016. Epub 2019 Sep 10. Allergy. 2020. PMID: 31506971 Free PMC article.
High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls.
Thun GA, Derdak S, Castro-Giner F, Apunte-Ramos K, Águeda L, Wjst M, Boland A, Deleuze JF, Kolsum U, Heiss-Neumann MS, Nowinski A, Gorecka D, Hohlfeld JM, Welte T, Brightling CE, Parr DG, Prasse A, Müller-Quernheim J, Greulich T, Stendardo M, Boschetto P, Barta I, Döme B, Gut M, Singh D, Ziegler-Heitbrock L, Gut IG. Thun GA, et al. Among authors: gut m, gut ig. Sci Rep. 2019 Dec 27;9(1):20158. doi: 10.1038/s41598-019-56618-1. Sci Rep. 2019. PMID: 31882973 Free PMC article.
Impact of DNA methylation on 3D genome structure.
Buitrago D, Labrador M, Arcon JP, Lema R, Flores O, Esteve-Codina A, Blanc J, Villegas N, Bellido D, Gut M, Dans PD, Heath SC, Gut IG, Brun Heath I, Orozco M. Buitrago D, et al. Among authors: gut m, gut ig. Nat Commun. 2021 May 28;12(1):3243. doi: 10.1038/s41467-021-23142-8. Nat Commun. 2021. PMID: 34050148 Free PMC article.
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes.
Esteve-Codina A, Hofer TP, Burggraf D, Heiss-Neumann MS, Gesierich W, Boland A, Olaso R, Bihoreau MT, Deleuze JF, Moeller W, Schmid O, Soler Artigas M, Renner K, Hohlfeld JM, Welte T, Fuehner T, Jerrentrup L, Koczulla AR, Greulich T, Prasse A, Müller-Quernheim J, Gupta S, Brightling C, Subramanian DR, Parr DG, Kolsum U, Gupta V, Barta I, Döme B, Strausz J, Stendardo M, Piattella M, Boschetto P, Korzybski D, Gorecka D, Nowinski A, Dabad M, Fernández-Callejo M, Endesfelder D, Zu Castell W, Hiemstra PS, Venge P, Noessner E, Griebel T, Heath S, Singh D, Gut I, Ziegler-Heitbrock L. Esteve-Codina A, et al. Among authors: gut i. Sci Rep. 2021 Jun 18;11(1):12848. doi: 10.1038/s41598-021-91742-x. Sci Rep. 2021. PMID: 34145303 Free PMC article.
489 results