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Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells.
Deveshegowda SN, Metri PK, Shivakumar R, Yang JR, Rangappa S, Swamynayaka A, Shanmugam MK, Nagaraja O, Madegowda M, Babu Shubha P, Chinnathambi A, Alharbi SA, Pandey V, Ahn KS, Lobie PE, Basappa B. Deveshegowda SN, et al. Among authors: shanmugam mk. Molecules. 2022 Apr 29;27(9):2848. doi: 10.3390/molecules27092848. Molecules. 2022. PMID: 35566199 Free PMC article.
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4.
Manu KA, Shanmugam MK, Rajendran P, Li F, Ramachandran L, Hay HS, Kannaiyan R, Swamy SN, Vali S, Kapoor S, Ramesh B, Bist P, Koay ES, Lim LH, Ahn KS, Kumar AP, Sethi G. Manu KA, et al. Among authors: shanmugam mk. Mol Cancer. 2011 Sep 1;10:107. doi: 10.1186/1476-4598-10-107. Mol Cancer. 2011. PMID: 21880153 Free PMC article.
Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G. Ramachandran L, et al. Among authors: shanmugam mk. J Biol Chem. 2012 Nov 2;287(45):38028-40. doi: 10.1074/jbc.M112.388702. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992727 Free PMC article.
Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.
Subramaniam A, Shanmugam MK, Perumal E, Li F, Nachiyappan A, Dai X, Swamy SN, Ahn KS, Kumar AP, Tan BK, Hui KM, Sethi G. Subramaniam A, et al. Among authors: shanmugam mk. Biochim Biophys Acta. 2013 Jan;1835(1):46-60. doi: 10.1016/j.bbcan.2012.10.002. Epub 2012 Oct 26. Biochim Biophys Acta. 2013. PMID: 23103770 Review.
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Subramaniam A, Loo SY, Rajendran P, Manu KA, Perumal E, Li F, Shanmugam MK, Siveen KS, Park JI, Ahn KS, Hui KM, Kumar AP, Sethi G. Subramaniam A, et al. Among authors: shanmugam mk. Apoptosis. 2013 Oct;18(10):1175-87. doi: 10.1007/s10495-013-0851-5. Apoptosis. 2013. PMID: 23700228
114 results