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c-FOS drives reversible basal to squamous cell carcinoma transition.
Kuonen F, Li NY, Haensel D, Patel T, Gaddam S, Yerly L, Rieger K, Aasi S, Oro AE. Kuonen F, et al. Among authors: oro ae. Cell Rep. 2021 Oct 5;37(1):109774. doi: 10.1016/j.celrep.2021.109774. Cell Rep. 2021. PMID: 34610301 Free PMC article.
Gibbin mesodermal regulation patterns epithelial development.
Collier A, Liu A, Torkelson J, Pattison J, Gaddam S, Zhen H, Patel T, McCarthy K, Ghanim H, Oro AE. Collier A, et al. Among authors: oro ae. Nature. 2022 Jun;606(7912):188-196. doi: 10.1038/s41586-022-04727-9. Epub 2022 May 18. Nature. 2022. PMID: 35585237 Free PMC article.
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Bartl J, Zanini M, Bernardi F, Forget A, Blümel L, Talbot J, Picard D, Qin N, Cancila G, Gao Q, Nath S, Koumba IM, Wolter M, Kuonen F, Langini M, Beez T, Munoz C, Pauck D, Marquardt V, Yu H, Souphron J, Korsch M, Mölders C, Berger D, Göbbels S, Meyer FD, Scheffler B, Rotblat B, Diederichs S, Ramaswamy V, Suzuki H, Oro A, Stühler K, Stefanski A, Fischer U, Leprivier G, Willbold D, Steger G, Buell A, Kool M, Lichter P, Pfister SM, Northcott PA, Taylor MD, Borkhardt A, Reifenberger G, Ayrault O, Remke M. Bartl J, et al. Nat Commun. 2022 Jul 13;13(1):4061. doi: 10.1038/s41467-022-31574-z. Nat Commun. 2022. PMID: 35831316 Free PMC article.
LY6D marks pre-existing resistant basosquamous tumor subpopulations.
Haensel D, Gaddam S, Li NY, Gonzalez F, Patel T, Cloutier JM, Sarin KY, Tang JY, Rieger KE, Aasi SZ, Oro AE. Haensel D, et al. Among authors: oro ae. Nat Commun. 2022 Dec 6;13(1):7520. doi: 10.1038/s41467-022-35020-y. Nat Commun. 2022. PMID: 36473848 Free PMC article.
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO. Sneddon JB, et al. Among authors: oro ae. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14842-7. doi: 10.1073/pnas.0606857103. Epub 2006 Sep 26. Proc Natl Acad Sci U S A. 2006. PMID: 17003113 Free PMC article.
110 results