Stachulski AV - Search Results

1

A host-gut microbial amino acid co-metabolite, p-cresol glucuronide, promotes blood-brain barrier integrity in vivo.

Stachulski AV, Knausenberger TB, Shah SN, Hoyles L, McArthur S. Stachulski AV, et al. Tissue Barriers. 2023 Jan 2;11(1):2073175. doi: 10.1080/21688370.2022.2073175. Epub 2022 May 20. Tissue Barriers. 2023. PMID: 35596559 Free PMC article.

2

Acyl glucuronide reactivity in perspective.

Bradshaw PR, Athersuch TJ, Stachulski AV, Wilson ID. Bradshaw PR, et al. Among authors: stachulski av. Drug Discov Today. 2020 Sep;25(9):1639-1650. doi: 10.1016/j.drudis.2020.07.009. Epub 2020 Jul 15. Drug Discov Today. 2020. PMID: 32681884 Free article. Review.

3

Synthesis and toxicity profile in 293 human embryonic kidney cells of the β D-glucuronide derivatives of ortho-, meta- and para-cresol.

London JA, Wang ECS, Barsukov IL, Yates EA, Stachulski AV. London JA, et al. Among authors: stachulski av. Carbohydr Res. 2021 Jan;499:108225. doi: 10.1016/j.carres.2020.108225. Epub 2020 Dec 17. Carbohydr Res. 2021. PMID: 33353664

4

Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis.

Meng X, Maggs JL, Pryde DC, Planken S, Jenkins RE, Peakman TM, Beaumont K, Kohl C, Park BK, Stachulski AV. Meng X, et al. Among authors: stachulski av. J Med Chem. 2007 Nov 29;50(24):6165-76. doi: 10.1021/jm0706766. Epub 2007 Nov 7. J Med Chem. 2007. PMID: 17985860

5

Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite.

O'Neill PM, Scheinmann F, Stachulski AV, Maggs JL, Park BK. O'Neill PM, et al. Among authors: stachulski av. J Med Chem. 2001 Apr 26;44(9):1467-70. doi: 10.1021/jm001061a. J Med Chem. 2001. PMID: 11311070

6

Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships.

Bradshaw PR, Richards SE, Wilson ID, Stachulski AV, Lindon JC, Athersuch TJ. Bradshaw PR, et al. Among authors: stachulski av. Org Biomol Chem. 2020 Feb 19;18(7):1389-1401. doi: 10.1039/c9ob02008j. Org Biomol Chem. 2020. PMID: 32002533

7

NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues.

Johnson CH, Wilson ID, Harding JR, Stachulski AV, Iddon L, Nicholson JK, Lindon JC. Johnson CH, et al. Among authors: stachulski av. Anal Chem. 2007 Nov 15;79(22):8720-7. doi: 10.1021/ac071368i. Epub 2007 Oct 18. Anal Chem. 2007. PMID: 17944439

8

Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.

Johnson CH, Karlsson E, Sarda S, Iddon L, Iqbal M, Meng X, Harding JR, Stachulski AV, Nicholson JK, Wilson ID, Lindon JC. Johnson CH, et al. Among authors: stachulski av. Xenobiotica. 2010 Jan;40(1):9-23. doi: 10.3109/00498250903348720. Xenobiotica. 2010. PMID: 19919325

9

High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma.

Karlsson ES, Johnson CH, Sarda S, Iddon L, Iqbal M, Meng X, Harding JR, Stachulski AV, Nicholson JK, Wilson ID, Lindon JC. Karlsson ES, et al. Among authors: stachulski av. Rapid Commun Mass Spectrom. 2010 Oct 30;24(20):3043-51. doi: 10.1002/rcm.4740. Rapid Commun Mass Spectrom. 2010. PMID: 20872637

10

The acyl nitroso Diels-Alder (ANDA) reaction of sorbate derivatives: an X-ray and 15N NMR study with an application to amino-acid synthesis.

Bollans L, Bacsa J, Iggo JA, Morris GA, Stachulski AV. Bollans L, et al. Among authors: stachulski av. Org Biomol Chem. 2009 Nov 7;7(21):4531-8. doi: 10.1039/b912963d. Epub 2009 Sep 2. Org Biomol Chem. 2009. PMID: 19830306

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