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Page 1
Wastewater-Based Estimation of the Effective Reproductive Number of SARS-CoV-2.
Huisman JS, Scire J, Caduff L, Fernandez-Cassi X, Ganesanandamoorthy P, Kull A, Scheidegger A, Stachler E, Boehm AB, Hughes B, Knudson A, Topol A, Wigginton KR, Wolfe MK, Kohn T, Ort C, Stadler T, Julian TR. Huisman JS, et al. Among authors: topol a. Environ Health Perspect. 2022 May;130(5):57011. doi: 10.1289/EHP10050. Epub 2022 May 26. Environ Health Perspect. 2022. PMID: 35617001 Free PMC article.
High-Frequency, High-Throughput Quantification of SARS-CoV-2 RNA in Wastewater Settled Solids at Eight Publicly Owned Treatment Works in Northern California Shows Strong Association with COVID-19 Incidence.
Wolfe MK, Topol A, Knudson A, Simpson A, White B, Vugia DJ, Yu AT, Li L, Balliet M, Stoddard P, Han GS, Wigginton KR, Boehm AB. Wolfe MK, et al. Among authors: topol a. mSystems. 2021 Oct 26;6(5):e0082921. doi: 10.1128/mSystems.00829-21. Epub 2021 Sep 14. mSystems. 2021. PMID: 34519528 Free PMC article.
SARS-CoV-2 RNA is enriched by orders of magnitude in primary settled solids relative to liquid wastewater at publicly owned treatment works.
Kim S, Kennedy LC, Wolfe MK, Criddle CS, Duong DH, Topol A, White BJ, Kantor RS, Nelson KL, Steele JA, Langlois K, Griffith JF, Zimmer-Faust AG, McLellan SL, Schussman MK, Ammerman M, Wigginton KR, Bakker KM, Boehm AB. Kim S, et al. Among authors: topol a. Environ Sci (Camb). 2022 Feb 15;8(4):757-770. doi: 10.1039/d1ew00826a. eCollection 2022 Mar 31. Environ Sci (Camb). 2022. PMID: 35433013 Free PMC article.
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia.
Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, Brennand KJ, Maze I. Farrelly LA, et al. Among authors: topol a. Nat Commun. 2022 Apr 22;13(1):2195. doi: 10.1038/s41467-022-29922-0. Nat Commun. 2022. PMID: 35459277 Free PMC article.
Synergistic effects of common schizophrenia risk variants.
Schrode N, Ho SM, Yamamuro K, Dobbyn A, Huckins L, Matos MR, Cheng E, Deans PJM, Flaherty E, Barretto N, Topol A, Alganem K, Abadali S, Gregory J, Hoelzli E, Phatnani H, Singh V, Girish D, Aronow B, Mccullumsmith R, Hoffman GE, Stahl EA, Morishita H, Sklar P, Brennand KJ. Schrode N, et al. Among authors: topol a. Nat Genet. 2019 Oct;51(10):1475-1485. doi: 10.1038/s41588-019-0497-5. Epub 2019 Sep 23. Nat Genet. 2019. PMID: 31548722 Free PMC article.
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D; CommonMind Consortium; Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK. Dobbyn A, et al. Am J Hum Genet. 2018 Jun 7;102(6):1169-1184. doi: 10.1016/j.ajhg.2018.04.011. Epub 2018 May 24. Am J Hum Genet. 2018. PMID: 29805045 Free PMC article.
Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.
Topol A, Zhu S, Hartley BJ, English J, Hauberg ME, Tran N, Rittenhouse CA, Simone A, Ruderfer DM, Johnson J, Readhead B, Hadas Y, Gochman PA, Wang YC, Shah H, Cagney G, Rapoport J, Gage FH, Dudley JT, Sklar P, Mattheisen M, Cotter D, Fang G, Brennand KJ. Topol A, et al. Cell Rep. 2017 Sep 5;20(10):2525. doi: 10.1016/j.celrep.2017.08.073. Cell Rep. 2017. PMID: 28877483 Free PMC article. No abstract available.
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P. Fromer M, et al. Among authors: topol a. Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038/nn.4399. Epub 2016 Sep 26. Nat Neurosci. 2016. PMID: 27668389 Free PMC article.
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.
Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, Rapoport J, Ellman JA, Pittenger C, Aronow B, Nairn AC, Nestor MW, Lombroso PJ, Brennand KJ. Xu J, et al. Among authors: topol a. Mol Psychiatry. 2018 Feb;23(2):271-281. doi: 10.1038/mp.2016.163. Epub 2016 Oct 18. Mol Psychiatry. 2018. PMID: 27752082 Free PMC article.
21 results