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Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).
Jefri M, Zhang X, Stumpf PS, Zhang L, Peng H, Hettige N, Theroux JF, Aouabed Z, Wilson K, Deshmukh S, Antonyan L, Ni A, Alsuwaidi S, Zhang Y, Jabado N, Garcia BA, Schuppert A, Bjornsson HT, Ernst C. Jefri M, et al. Among authors: schuppert a. Hum Mol Genet. 2022 Oct 28;31(21):3715-3728. doi: 10.1093/hmg/ddac121. Hum Mol Genet. 2022. PMID: 35640156 Free PMC article.
Stem Cell Differentiation as a Non-Markov Stochastic Process.
Stumpf PS, Smith RCG, Lenz M, Schuppert A, Müller FJ, Babtie A, Chan TE, Stumpf MPH, Please CP, Howison SD, Arai F, MacArthur BD. Stumpf PS, et al. Among authors: schuppert a. Cell Syst. 2017 Sep 27;5(3):268-282.e7. doi: 10.1016/j.cels.2017.08.009. Cell Syst. 2017. PMID: 28957659 Free PMC article.
Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.
Jefri M, Bell S, Peng H, Hettige N, Maussion G, Soubannier V, Wu H, Silveira H, Theroux JF, Moquin L, Zhang X, Aouabed Z, Krishnan J, O'Leary LA, Antonyan L, Zhang Y, McCarty V, Mechawar N, Gratton A, Schuppert A, Durcan TM, Fon EA, Ernst C. Jefri M, et al. Among authors: schuppert a. Stem Cells Transl Med. 2020 Jun;9(6):697-712. doi: 10.1002/sctm.18-0180. Epub 2020 Mar 10. Stem Cells Transl Med. 2020. PMID: 32154672 Free PMC article.
Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells.
Bell S, McCarty V, Peng H, Jefri M, Hettige N, Antonyan L, Crapper L, O'Leary LA, Zhang X, Zhang Y, Wu H, Sutcliffe D, Kolobova I, Rosenberger TA, Moquin L, Gratton A, Popic J, Gantois I, Stumpf PS, Schuppert AA, Mechawar N, Sonenberg N, Tremblay ML, Jinnah HA, Ernst C. Bell S, et al. Among authors: schuppert aa. Stem Cell Reports. 2021 Jul 13;16(7):1749-1762. doi: 10.1016/j.stemcr.2021.06.003. Epub 2021 Jul 1. Stem Cell Reports. 2021. PMID: 34214487 Free PMC article.
FOXG1 dose tunes cell proliferation dynamics in human forebrain progenitor cells.
Hettige NC, Peng H, Wu H, Zhang X, Yerko V, Zhang Y, Jefri M, Soubannier V, Maussion G, Alsuwaidi S, Ni A, Rocha C, Krishnan J, McCarty V, Antonyan L, Schuppert A, Turecki G, Fon EA, Durcan TM, Ernst C. Hettige NC, et al. Among authors: schuppert a. Stem Cell Reports. 2022 Mar 8;17(3):475-488. doi: 10.1016/j.stemcr.2022.01.010. Epub 2022 Feb 10. Stem Cell Reports. 2022. PMID: 35148845 Free PMC article.
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.
MacArthur BD, Sevilla A, Lenz M, Müller FJ, Schuldt BM, Schuppert AA, Ridden SJ, Stumpf PS, Fidalgo M, Ma'ayan A, Wang J, Lemischka IR. MacArthur BD, et al. Among authors: schuppert aa. Nat Cell Biol. 2012 Nov;14(11):1139-47. doi: 10.1038/ncb2603. Epub 2012 Oct 28. Nat Cell Biol. 2012. PMID: 23103910 Free PMC article.
Few inputs can reprogram biological networks.
Müller FJ, Schuppert A. Müller FJ, et al. Among authors: schuppert a. Nature. 2011 Oct 19;478(7369):E4; discussion E4-5. doi: 10.1038/nature10543. Nature. 2011. PMID: 22012402 No abstract available.
Power-laws and the use of pluripotent stem cell lines.
Schuldt BM, Guhr A, Lenz M, Kobold S, MacArthur BD, Schuppert A, Löser P, Müller FJ. Schuldt BM, et al. Among authors: schuppert a. PLoS One. 2013;8(1):e52068. doi: 10.1371/journal.pone.0052068. Epub 2013 Jan 2. PLoS One. 2013. PMID: 23300961 Free PMC article.
67 results