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Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.
Korsunsky I, Wei K, Pohin M, Kim EY, Barone F, Major T, Taylor E, Ravindran R, Kemble S, Watts GFM, Jonsson AH, Jeong Y, Athar H, Windell D, Kang JB, Friedrich M, Turner J, Nayar S, Fisher BA, Raza K, Marshall JL, Croft AP, Tamura T, Sholl LM, Vivero M, Rosas IO, Bowman SJ, Coles M, Frei AP, Lassen K, Filer A, Powrie F, Buckley CD, Brenner MB, Raychaudhuri S. Korsunsky I, et al. Among authors: coles m. Med. 2022 Jul 8;3(7):481-518.e14. doi: 10.1016/j.medj.2022.05.002. Epub 2022 May 31. Med. 2022. PMID: 35649411 Free PMC article.
IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma.
Pandey S, Mourcin F, Marchand T, Nayar S, Guirriec M, Pangault C, Monvoisin C, Amé-Thomas P, Guilloton F, Dulong J, Coles M, Fest T, Mottok A, Barone F, Tarte K. Pandey S, et al. Among authors: coles m. Blood. 2017 May 4;129(18):2507-2518. doi: 10.1182/blood-2016-08-737239. Epub 2017 Feb 15. Blood. 2017. PMID: 28202459 Free article.
Distinct fibroblast subsets drive inflammation and damage in arthritis.
Croft AP, Campos J, Jansen K, Turner JD, Marshall J, Attar M, Savary L, Wehmeyer C, Naylor AJ, Kemble S, Begum J, Dürholz K, Perlman H, Barone F, McGettrick HM, Fearon DT, Wei K, Raychaudhuri S, Korsunsky I, Brenner MB, Coles M, Sansom SN, Filer A, Buckley CD. Croft AP, et al. Among authors: coles m. Nature. 2019 Jun;570(7760):246-251. doi: 10.1038/s41586-019-1263-7. Epub 2019 May 29. Nature. 2019. PMID: 31142839 Free PMC article.
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology.
Nayar S, Campos J, Smith CG, Iannizzotto V, Gardner DH, Mourcin F, Roulois D, Turner J, Sylvestre M, Asam S, Glaysher B, Bowman SJ, Fearon DT, Filer A, Tarte K, Luther SA, Fisher BA, Buckley CD, Coles MC, Barone F. Nayar S, et al. Among authors: coles mc. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13490-13497. doi: 10.1073/pnas.1905301116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213547 Free PMC article.
Ready-made cellular plugs heal skin wounds.
Coles MC, Buckley CD. Coles MC, et al. Nature. 2019 Dec;576(7786):215-216. doi: 10.1038/d41586-019-03602-4. Nature. 2019. PMID: 31822827 No abstract available.
Fibroblasts as immune regulators in infection, inflammation and cancer.
Davidson S, Coles M, Thomas T, Kollias G, Ludewig B, Turley S, Brenner M, Buckley CD. Davidson S, et al. Among authors: coles m. Nat Rev Immunol. 2021 Nov;21(11):704-717. doi: 10.1038/s41577-021-00540-z. Epub 2021 Apr 28. Nat Rev Immunol. 2021. PMID: 33911232 Review.
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.
Friedrich M, Pohin M, Jackson MA, Korsunsky I, Bullers SJ, Rue-Albrecht K, Christoforidou Z, Sathananthan D, Thomas T, Ravindran R, Tandon R, Peres RS, Sharpe H, Wei K, Watts GFM, Mann EH, Geremia A, Attar M; Oxford IBD Cohort Investigators; Roche Fibroblast Network Consortium; McCuaig S, Thomas L, Collantes E, Uhlig HH, Sansom SN, Easton A, Raychaudhuri S, Travis SP, Powrie FM. Friedrich M, et al. Nat Med. 2021 Nov;27(11):1970-1981. doi: 10.1038/s41591-021-01520-5. Epub 2021 Oct 21. Nat Med. 2021. PMID: 34675383 Free PMC article.
The Cellular Composition of the Uveal Immune Environment.
Reekie IR, Sharma S, Foers A, Sherlock J, Coles MC, Dick AD, Denniston AK, Buckley CD. Reekie IR, et al. Front Med (Lausanne). 2021 Oct 29;8:721953. doi: 10.3389/fmed.2021.721953. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34778287 Free PMC article. Review.
609 results