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Using genetic variation to disentangle the complex relationship between food intake and health outcomes.
Pirastu N, McDonnell C, Grzeszkowiak EJ, Mounier N, Imamura F, Merino J, Day FR, Zheng J, Taba N, Concas MP, Repetto L, Kentistou KA, Robino A, Esko T, Joshi PK, Fischer K, Ong KK, Gaunt TR, Kutalik Z, Perry JRB, Wilson JF. Pirastu N, et al. Among authors: imamura f. PLoS Genet. 2022 Jun 2;18(6):e1010162. doi: 10.1371/journal.pgen.1010162. eCollection 2022 Jun. PLoS Genet. 2022. PMID: 35653391 Free PMC article.
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.
Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sjögren RJ, Näslund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O'Rahilly S, Wareham NJ, Langenberg C. Lotta LA, et al. Among authors: imamura f. PLoS Med. 2016 Nov 29;13(11):e1002179. doi: 10.1371/journal.pmed.1002179. eCollection 2016 Nov. PLoS Med. 2016. PMID: 27898682 Free PMC article.
Assessing the causal association of glycine with risk of cardio-metabolic diseases.
Wittemans LBL, Lotta LA, Oliver-Williams C, Stewart ID, Surendran P, Karthikeyan S, Day FR, Koulman A, Imamura F, Zeng L, Erdmann J, Schunkert H, Khaw KT, Griffin JL, Forouhi NG, Scott RA, Wood AM, Burgess S, Howson JMM, Danesh J, Wareham NJ, Butterworth AS, Langenberg C. Wittemans LBL, et al. Among authors: imamura f. Nat Commun. 2019 Mar 5;10(1):1060. doi: 10.1038/s41467-019-08936-1. Nat Commun. 2019. PMID: 30837465 Free PMC article.
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
Zheng JS, Luan J, Sofianopoulou E, Sharp SJ, Day FR, Imamura F, Gundersen TE, Lotta LA, Sluijs I, Stewart ID, Shah RL, van der Schouw YT, Wheeler E, Ardanaz E, Boeing H, Dorronsoro M, Dahm CC, Dimou N, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Huerta JM, Heath AK, Hansen L, Jenab M, Jakszyn P, Kaaks R, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Olsen A, Panico S, Quirós JR, Rolandsson O, Rodríguez-Barranco M, Sacerdote C, Spijkerman AMW, Tong TYN, Tumino R, Tsilidis KK, Danesh J, Riboli E, Butterworth AS, Langenberg C, Forouhi NG, Wareham NJ. Zheng JS, et al. Among authors: imamura f. PLoS Med. 2020 Oct 16;17(10):e1003394. doi: 10.1371/journal.pmed.1003394. eCollection 2020 Oct. PLoS Med. 2020. PMID: 33064751 Free PMC article.
Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study.
Vissers LET, Sluijs I, van der Schouw YT, Forouhi NG, Imamura F, Burgess S, Barricarte A, Boeing H, Bonet C, Chirlaque MD, Fagherazzi G, Franks PW, Freisling H, Gunter MJ, Quirós JR, Ibsen DB, Kaaks R, Key T, Khaw KT, Kühn T, Mokoroa O, Nilsson PM, Overvad K, Pala V, Palli D, Panico S, Sacerdote C, Spijkerman AMW, Tjonneland A, Tumino R, Rodríguez-Barranco M, Rolandsson O, Riboli E, Sharp SJ, Langenberg C, Wareham NJ. Vissers LET, et al. Among authors: imamura f. Diabetes Care. 2019 Apr;42(4):568-575. doi: 10.2337/dc18-2034. Epub 2019 Feb 6. Diabetes Care. 2019. PMID: 30728219 Free PMC article.
Genomic analysis of diet composition finds novel loci and associations with health and lifestyle.
Meddens SFW, de Vlaming R, Bowers P, Burik CAP, Linnér RK, Lee C, Okbay A, Turley P, Rietveld CA, Fontana MA, Ghanbari M, Imamura F, McMahon G, van der Most PJ, Voortman T, Wade KH, Anderson EL, Braun KVE, Emmett PM, Esko T, Gonzalez JR, Kiefte-de Jong JC, Langenberg C, Luan J, Muka T, Ring S, Rivadeneira F, Snieder H, van Rooij FJA, Wolffenbuttel BHR; 23andMe Research Team; EPIC- InterAct Consortium; Lifelines Cohort Study; Smith GD, Franco OH, Forouhi NG, Ikram MA, Uitterlinden AG, van Vliet-Ostaptchouk JV, Wareham NJ, Cesarini D, Harden KP, Lee JJ, Benjamin DJ, Chow CC, Koellinger PD. Meddens SFW, et al. Among authors: imamura f. Mol Psychiatry. 2021 Jun;26(6):2056-2069. doi: 10.1038/s41380-020-0697-5. Epub 2020 May 11. Mol Psychiatry. 2021. PMID: 32393786 Free PMC article.
Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.
Zheng JS, Luan J, Sofianopoulou E, Imamura F, Stewart ID, Day FR, Pietzner M, Wheeler E, Lotta LA, Gundersen TE, Amiano P, Ardanaz E, Chirlaque MD, Fagherazzi G, Franks PW, Kaaks R, Laouali N, Mancini FR, Nilsson PM, Onland-Moret NC, Olsen A, Overvad K, Panico S, Palli D, Ricceri F, Rolandsson O, Spijkerman AMW, Sánchez MJ, Schulze MB, Sala N, Sieri S, Tjønneland A, Tumino R, van der Schouw YT, Weiderpass E, Riboli E, Danesh J, Butterworth AS, Sharp SJ, Langenberg C, Forouhi NG, Wareham NJ. Zheng JS, et al. Among authors: imamura f. Diabetes Care. 2021 Jan;44(1):98-106. doi: 10.2337/dc20-1328. Epub 2020 Nov 17. Diabetes Care. 2021. PMID: 33203707 Free PMC article.
A cross-platform approach identifies genetic regulators of human metabolism and health.
Lotta LA, Pietzner M, Stewart ID, Wittemans LBL, Li C, Bonelli R, Raffler J, Biggs EK, Oliver-Williams C, Auyeung VPW, Luan J, Wheeler E, Paige E, Surendran P, Michelotti GA, Scott RA, Burgess S, Zuber V, Sanderson E, Koulman A, Imamura F, Forouhi NG, Khaw KT; MacTel Consortium; Griffin JL, Wood AM, Kastenmüller G, Danesh J, Butterworth AS, Gribble FM, Reimann F, Bahlo M, Fauman E, Wareham NJ, Langenberg C. Lotta LA, et al. Among authors: imamura f. Nat Genet. 2021 Jan;53(1):54-64. doi: 10.1038/s41588-020-00751-5. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414548 Free PMC article.
402 results